A ratiometric electrochemical sensor for selectively monitoring monoamine oxidase A in the live brain

Chuanping Zhang; Chenxiao Tang; Yuxiao Mei; Limin Zhang; Anwei Zhu; Yang Tian

doi:10.1039/d1cc00787d

A ratiometric electrochemical sensor for selectively monitoring monoamine oxidase A in the live brain

Chuanping Zhang
, Chenxiao Tang
, Yuxiao Mei
, Limin Zhang
, Anwei Zhu^*
, Yang Tian

^*此作品的通讯作者

化学与分子工程学院

East China Normal University

科研成果: 期刊稿件 › 文章 › 同行评审

6 引用（Scopus）

摘要

Herein, an electrochemical method for selectively sensing and accurately quantifying monoamine oxidase A (MAO-A) in the cortex and thalamus of a live mouse brain was reported. Using this tool, it was found that MAO-A increased Ca²⁺entry into neuronsviathe TPRM2 channel in the live mouse brain of an AD model.

源语言	英语
页（从-至）	6487-6490
页数	4
期刊	Chemical Communications
卷	57
期	53
DOI	https://doi.org/10.1039/d1cc00787d
出版状态	已出版 - 7 7月 2021

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10.1039/d1cc00787d

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引用此

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title = "A ratiometric electrochemical sensor for selectively monitoring monoamine oxidase A in the live brain",

abstract = "Herein, an electrochemical method for selectively sensing and accurately quantifying monoamine oxidase A (MAO-A) in the cortex and thalamus of a live mouse brain was reported. Using this tool, it was found that MAO-A increased Ca2+entry into neuronsviathe TPRM2 channel in the live mouse brain of an AD model.",

author = "Chuanping Zhang and Chenxiao Tang and Yuxiao Mei and Limin Zhang and Anwei Zhu and Yang Tian",

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AU - Zhang, Chuanping

AU - Tang, Chenxiao

AU - Mei, Yuxiao

AU - Zhang, Limin

AU - Zhu, Anwei

AU - Tian, Yang

PY - 2021/7/7

Y1 - 2021/7/7

N2 - Herein, an electrochemical method for selectively sensing and accurately quantifying monoamine oxidase A (MAO-A) in the cortex and thalamus of a live mouse brain was reported. Using this tool, it was found that MAO-A increased Ca2+entry into neuronsviathe TPRM2 channel in the live mouse brain of an AD model.

AB - Herein, an electrochemical method for selectively sensing and accurately quantifying monoamine oxidase A (MAO-A) in the cortex and thalamus of a live mouse brain was reported. Using this tool, it was found that MAO-A increased Ca2+entry into neuronsviathe TPRM2 channel in the live mouse brain of an AD model.

UR - https://www.scopus.com/pages/publications/85109007680

U2 - 10.1039/d1cc00787d

DO - 10.1039/d1cc00787d

M3 - 文章

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AN - SCOPUS:85109007680

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VL - 57

SP - 6487

EP - 6490

JO - Chemical Communications

JF - Chemical Communications

IS - 53

ER -

A ratiometric electrochemical sensor for selectively monitoring monoamine oxidase A in the live brain

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