A near-infrared fluorescent probe for rapid detection of hydrogen peroxide in living cells

Xuan Zhang; Lun Zhang; Yaqian Liu; Bin Bao; Yi Zang; Jia Li; Wei Lu

doi:10.1016/j.tet.2015.05.025

A near-infrared fluorescent probe for rapid detection of hydrogen peroxide in living cells

Xuan Zhang
, Lun Zhang
, Yaqian Liu
, Bin Bao
, Yi Zang
, Jia Li^*
, Wei Lu

^*此作品的通讯作者

化学与分子工程学院

科研成果: 期刊稿件 › 文章 › 同行评审

41 引用（Scopus）

摘要

A new near-infrared and colorimetric fluorescent molecular probe was developed for rapid detection of H₂O₂. The near-infrared fluorescence OFF-ON switch is triggered by transformation of phenylboronic acid unit to phenol in the presence of H₂O₂. No quinone methides are released in this process, which is preferable for in vivo studies. In addition, probe 1 at low concentration exhibits high quality optical imaging during a short period in in vitro cell study.

源语言	英语
页（从-至）	4842-4845
页数	4
期刊	Tetrahedron
卷	71
期	29
DOI	https://doi.org/10.1016/j.tet.2015.05.025
出版状态	已出版 - 2015

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title = "A near-infrared fluorescent probe for rapid detection of hydrogen peroxide in living cells",

abstract = "A new near-infrared and colorimetric fluorescent molecular probe was developed for rapid detection of H2O2. The near-infrared fluorescence OFF-ON switch is triggered by transformation of phenylboronic acid unit to phenol in the presence of H2O2. No quinone methides are released in this process, which is preferable for in vivo studies. In addition, probe 1 at low concentration exhibits high quality optical imaging during a short period in in vitro cell study.",

keywords = "Hydrogen peroxide, Near-infrared, Probe, ROS",

author = "Xuan Zhang and Lun Zhang and Yaqian Liu and Bin Bao and Yi Zang and Jia Li and Wei Lu",

year = "2015",

doi = "10.1016/j.tet.2015.05.025",

language = "英语",

volume = "71",

pages = "4842--4845",

journal = "Tetrahedron",

issn = "0040-4020",

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TY - JOUR

T1 - A near-infrared fluorescent probe for rapid detection of hydrogen peroxide in living cells

AU - Zhang, Xuan

AU - Zhang, Lun

AU - Liu, Yaqian

AU - Bao, Bin

AU - Zang, Yi

AU - Li, Jia

AU - Lu, Wei

PY - 2015

Y1 - 2015

N2 - A new near-infrared and colorimetric fluorescent molecular probe was developed for rapid detection of H2O2. The near-infrared fluorescence OFF-ON switch is triggered by transformation of phenylboronic acid unit to phenol in the presence of H2O2. No quinone methides are released in this process, which is preferable for in vivo studies. In addition, probe 1 at low concentration exhibits high quality optical imaging during a short period in in vitro cell study.

AB - A new near-infrared and colorimetric fluorescent molecular probe was developed for rapid detection of H2O2. The near-infrared fluorescence OFF-ON switch is triggered by transformation of phenylboronic acid unit to phenol in the presence of H2O2. No quinone methides are released in this process, which is preferable for in vivo studies. In addition, probe 1 at low concentration exhibits high quality optical imaging during a short period in in vitro cell study.

KW - Hydrogen peroxide

KW - Near-infrared

KW - Probe

KW - ROS

UR - https://www.scopus.com/pages/publications/84937152419

U2 - 10.1016/j.tet.2015.05.025

DO - 10.1016/j.tet.2015.05.025

M3 - 文章

AN - SCOPUS:84937152419

SN - 0040-4020

VL - 71

SP - 4842

EP - 4845

JO - Tetrahedron

JF - Tetrahedron

IS - 29

ER -

A near-infrared fluorescent probe for rapid detection of hydrogen peroxide in living cells

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