A highly sensitive long-wavelength fluorescence probe for nitroreductase and hypoxia: Selective detection and quantification

Ting Guo; Lei Cui; Jiaoning Shen; Weiping Zhu; Yufang Xu; Xuhong Qian

doi:10.1039/c3cc45367g

A highly sensitive long-wavelength fluorescence probe for nitroreductase and hypoxia: Selective detection and quantification

Ting Guo
, Lei Cui
, Jiaoning Shen
, Weiping Zhu
, Yufang Xu^*
, Xuhong Qian

^*此作品的通讯作者

East China University of Science and Technology

科研成果: 期刊稿件 › 文章 › 同行评审

127 引用（Scopus）

摘要

A novel long-wavelength fluorescence probe NBP has been developed for the detection of nitroreductase (NTR) and hypoxia. NBP could be activated by NTR at 0.1 μM to release the fluorophore NBF and significant changes in fluorescence emission at 658 nm were observed. This feature makes it advantageous for imaging hypoxic cells with minimal endogenous interference.

源语言	英语
页（从-至）	10820-10822
页数	3
期刊	Chemical Communications
卷	49
期	92
DOI	https://doi.org/10.1039/c3cc45367g
出版状态	已出版 - 24 10月 2013
已对外发布	是

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10.1039/c3cc45367g

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title = "A highly sensitive long-wavelength fluorescence probe for nitroreductase and hypoxia: Selective detection and quantification",

abstract = "A novel long-wavelength fluorescence probe NBP has been developed for the detection of nitroreductase (NTR) and hypoxia. NBP could be activated by NTR at 0.1 μM to release the fluorophore NBF and significant changes in fluorescence emission at 658 nm were observed. This feature makes it advantageous for imaging hypoxic cells with minimal endogenous interference.",

author = "Ting Guo and Lei Cui and Jiaoning Shen and Weiping Zhu and Yufang Xu and Xuhong Qian",

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T1 - A highly sensitive long-wavelength fluorescence probe for nitroreductase and hypoxia

T2 - Selective detection and quantification

AU - Guo, Ting

AU - Cui, Lei

AU - Shen, Jiaoning

AU - Zhu, Weiping

AU - Xu, Yufang

AU - Qian, Xuhong

PY - 2013/10/24

Y1 - 2013/10/24

N2 - A novel long-wavelength fluorescence probe NBP has been developed for the detection of nitroreductase (NTR) and hypoxia. NBP could be activated by NTR at 0.1 μM to release the fluorophore NBF and significant changes in fluorescence emission at 658 nm were observed. This feature makes it advantageous for imaging hypoxic cells with minimal endogenous interference.

AB - A novel long-wavelength fluorescence probe NBP has been developed for the detection of nitroreductase (NTR) and hypoxia. NBP could be activated by NTR at 0.1 μM to release the fluorophore NBF and significant changes in fluorescence emission at 658 nm were observed. This feature makes it advantageous for imaging hypoxic cells with minimal endogenous interference.

UR - https://www.scopus.com/pages/publications/84886544663

U2 - 10.1039/c3cc45367g

DO - 10.1039/c3cc45367g

M3 - 文章

C2 - 24121427

AN - SCOPUS:84886544663

SN - 1359-7345

VL - 49

SP - 10820

EP - 10822

JO - Chemical Communications

JF - Chemical Communications

IS - 92

ER -

A highly sensitive long-wavelength fluorescence probe for nitroreductase and hypoxia: Selective detection and quantification

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