A Highly Efficient Gold(I)-Catalyzed Mukaiyama-Mannich Reaction of α-Amino Sulfones with Fluorinated Silyl Enol Ethers to Give β-Amino α-Fluorinated Ketones

Xiao Si Hu; Yi Du; Jin Sheng Yu; Fu Min Liao; Pei Gang Ding; Jian Zhou

doi:10.1055/s-0036-1588475

A Highly Efficient Gold(I)-Catalyzed Mukaiyama-Mannich Reaction of α-Amino Sulfones with Fluorinated Silyl Enol Ethers to Give β-Amino α-Fluorinated Ketones

Xiao Si Hu
, Yi Du
, Jin Sheng Yu^*
, Fu Min Liao
, Pei Gang Ding
, Jian Zhou

^*此作品的通讯作者

化学与分子工程学院

科研成果: 期刊稿件 › 文章 › 同行评审

25 引用（Scopus）

摘要

Ph ₃ PAuOTf was identified as a powerful catalyst for the Mukaiyama-Mannich reaction of fluorinated silyl enol ethers with α-amino sulfones. This provides ready access to β-amino α-fluorinated ketones in good to excellent yields.

源语言	英语
页（从-至）	2194-2198
页数	5
期刊	Synlett
卷	28
期	16
DOI	https://doi.org/10.1055/s-0036-1588475
出版状态	已出版 - 2017

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@article{cc0bf9a392f84857bfd6fa991afd7bfa,

title = "A Highly Efficient Gold(I)-Catalyzed Mukaiyama-Mannich Reaction of α-Amino Sulfones with Fluorinated Silyl Enol Ethers to Give β-Amino α-Fluorinated Ketones",

abstract = "Ph 3 PAuOTf was identified as a powerful catalyst for the Mukaiyama-Mannich reaction of fluorinated silyl enol ethers with α-amino sulfones. This provides ready access to β-amino α-fluorinated ketones in good to excellent yields.",

keywords = "Mukaiyama-Mannich reaction, amino fluorinated ketones, amino sulfones, fluorinated silyl enol ethers, gold catalysis",

author = "Hu, \{Xiao Si\} and Yi Du and Yu, \{Jin Sheng\} and Liao, \{Fu Min\} and Ding, \{Pei Gang\} and Jian Zhou",

note = "Publisher Copyright: {\textcopyright} 2017 Georg Thieme Verlag Stuttgart. New York.",

year = "2017",

doi = "10.1055/s-0036-1588475",

language = "英语",

volume = "28",

pages = "2194--2198",

journal = "Synlett",

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publisher = "Georg Thieme Verlag",

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TY - JOUR

T1 - A Highly Efficient Gold(I)-Catalyzed Mukaiyama-Mannich Reaction of α-Amino Sulfones with Fluorinated Silyl Enol Ethers to Give β-Amino α-Fluorinated Ketones

AU - Hu, Xiao Si

AU - Du, Yi

AU - Yu, Jin Sheng

AU - Liao, Fu Min

AU - Ding, Pei Gang

AU - Zhou, Jian

PY - 2017

Y1 - 2017

N2 - Ph 3 PAuOTf was identified as a powerful catalyst for the Mukaiyama-Mannich reaction of fluorinated silyl enol ethers with α-amino sulfones. This provides ready access to β-amino α-fluorinated ketones in good to excellent yields.

AB - Ph 3 PAuOTf was identified as a powerful catalyst for the Mukaiyama-Mannich reaction of fluorinated silyl enol ethers with α-amino sulfones. This provides ready access to β-amino α-fluorinated ketones in good to excellent yields.

KW - Mukaiyama-Mannich reaction

KW - amino fluorinated ketones

KW - amino sulfones

KW - fluorinated silyl enol ethers

KW - gold catalysis

UR - https://www.scopus.com/pages/publications/85023751651

U2 - 10.1055/s-0036-1588475

DO - 10.1055/s-0036-1588475

M3 - 文章

AN - SCOPUS:85023751651

SN - 0936-5214

VL - 28

SP - 2194

EP - 2198

JO - Synlett

JF - Synlett

IS - 16

ER -

A Highly Efficient Gold(I)-Catalyzed Mukaiyama-Mannich Reaction of α-Amino Sulfones with Fluorinated Silyl Enol Ethers to Give β-Amino α-Fluorinated Ketones

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