A DNA nanostructure-based biomolecular probe carrier platform for electrochemical biosensing

Hao Pei; Na Lu; Yanli Wen; Shiping Song; Yan Liu; Hao Yan; Chunhai Fan

doi:10.1002/adma.201002767

A DNA nanostructure-based biomolecular probe carrier platform for electrochemical biosensing

Hao Pei^*
, Na Lu
, Yanli Wen
, Shiping Song
, Yan Liu
, Hao Yan
, Chunhai Fan

^*此作品的通讯作者

Chinese Academy of Sciences
Arizona State University

科研成果: 期刊稿件 › 文章 › 同行评审

533 引用（Scopus）

摘要

A 3D DNA nanostructure-based sensor platform for DNA detection has been developed. This strategy provides significantly enhanced spatial positioning range and accessibility of the probes on a surface over previously reported DNA sensing architectures. The use of this versatile DNA nanostructure-based detection platform leads to highly sensitive and selective DNA detection in biological fluids and greatly enhanced sequence specificity for SNP typing.

源语言	英语
页（从-至）	4754-4758
页数	5
期刊	Advanced Materials
卷	22
期	42
DOI	https://doi.org/10.1002/adma.201002767
出版状态	已出版 - 9 11月 2010
已对外发布	是

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10.1002/adma.201002767

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title = "A DNA nanostructure-based biomolecular probe carrier platform for electrochemical biosensing",

abstract = "A 3D DNA nanostructure-based sensor platform for DNA detection has been developed. This strategy provides significantly enhanced spatial positioning range and accessibility of the probes on a surface over previously reported DNA sensing architectures. The use of this versatile DNA nanostructure-based detection platform leads to highly sensitive and selective DNA detection in biological fluids and greatly enhanced sequence specificity for SNP typing.",

keywords = "Aptamer, DNA hybridization, DNA nanotechnology, Electrochemical DNA sensor, Single nucleotide polymorphism",

author = "Hao Pei and Na Lu and Yanli Wen and Shiping Song and Yan Liu and Hao Yan and Chunhai Fan",

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AU - Pei, Hao

AU - Lu, Na

AU - Wen, Yanli

AU - Song, Shiping

AU - Liu, Yan

AU - Yan, Hao

AU - Fan, Chunhai

PY - 2010/11/9

Y1 - 2010/11/9

N2 - A 3D DNA nanostructure-based sensor platform for DNA detection has been developed. This strategy provides significantly enhanced spatial positioning range and accessibility of the probes on a surface over previously reported DNA sensing architectures. The use of this versatile DNA nanostructure-based detection platform leads to highly sensitive and selective DNA detection in biological fluids and greatly enhanced sequence specificity for SNP typing.

AB - A 3D DNA nanostructure-based sensor platform for DNA detection has been developed. This strategy provides significantly enhanced spatial positioning range and accessibility of the probes on a surface over previously reported DNA sensing architectures. The use of this versatile DNA nanostructure-based detection platform leads to highly sensitive and selective DNA detection in biological fluids and greatly enhanced sequence specificity for SNP typing.

KW - Aptamer

KW - DNA hybridization

KW - DNA nanotechnology

KW - Electrochemical DNA sensor

KW - Single nucleotide polymorphism

UR - https://www.scopus.com/pages/publications/78149436155

U2 - 10.1002/adma.201002767

DO - 10.1002/adma.201002767

M3 - 文章

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AN - SCOPUS:78149436155

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A DNA nanostructure-based biomolecular probe carrier platform for electrochemical biosensing

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