A convenient synthesis of the immunosuppressive agent FTY720

Xiangjun Feng; Yuhua Mei; Yu Luo; Wei Lu

doi:10.1007/s00706-011-0582-7

A convenient synthesis of the immunosuppressive agent FTY720

Xiangjun Feng
, Yuhua Mei
, Yu Luo^*
, Wei Lu

^*此作品的通讯作者

化学与分子工程学院

East China Normal University

科研成果: 期刊稿件 › 文章 › 同行评审

12 引用（Scopus）

摘要

This paper describes a practical synthetic approach to preparation of an immunosuppressant, FTY720. The key steps involve an iron-catalyzed cross-coupling reaction and a Wittig reaction. The advantages of this synthesis include readily available starting materials, inexpensive reagents, simple operations and good yields.

源语言	英语
页（从-至）	161-164
页数	4
期刊	Monatshefte fur Chemie
卷	143
期	1
DOI	https://doi.org/10.1007/s00706-011-0582-7
出版状态	已出版 - 1月 2012

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@article{8f405263bd744381a1556ccb8f94cec8,

title = "A convenient synthesis of the immunosuppressive agent FTY720",

abstract = "This paper describes a practical synthetic approach to preparation of an immunosuppressant, FTY720. The key steps involve an iron-catalyzed cross-coupling reaction and a Wittig reaction. The advantages of this synthesis include readily available starting materials, inexpensive reagents, simple operations and good yields.",

keywords = "FTY720, Immunosuppressant, Iron-catalyzed, Synthesis, Wittig reaction",

author = "Xiangjun Feng and Yuhua Mei and Yu Luo and Wei Lu",

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T1 - A convenient synthesis of the immunosuppressive agent FTY720

AU - Feng, Xiangjun

AU - Mei, Yuhua

AU - Luo, Yu

AU - Lu, Wei

PY - 2012/1

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N2 - This paper describes a practical synthetic approach to preparation of an immunosuppressant, FTY720. The key steps involve an iron-catalyzed cross-coupling reaction and a Wittig reaction. The advantages of this synthesis include readily available starting materials, inexpensive reagents, simple operations and good yields.

AB - This paper describes a practical synthetic approach to preparation of an immunosuppressant, FTY720. The key steps involve an iron-catalyzed cross-coupling reaction and a Wittig reaction. The advantages of this synthesis include readily available starting materials, inexpensive reagents, simple operations and good yields.

KW - FTY720

KW - Immunosuppressant

KW - Iron-catalyzed

KW - Synthesis

KW - Wittig reaction

UR - https://www.scopus.com/pages/publications/84858861934

U2 - 10.1007/s00706-011-0582-7

DO - 10.1007/s00706-011-0582-7

M3 - 文章

AN - SCOPUS:84858861934

SN - 0026-9247

VL - 143

SP - 161

EP - 164

JO - Monatshefte fur Chemie

JF - Monatshefte fur Chemie

IS - 1

ER -

A convenient synthesis of the immunosuppressive agent FTY720

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