A 48-Day-Duration Pasting Bioelectronic Device Realizing Closed-Loop Realtime Detection and Precision Treatment for Type-1 Diabetes

Xiaoyuan Wu; Kangjie Zhao; Mengyao Liu; Shixiang Ding; Xuyang Li; Yuri Lu; Ruohan Wang; Ziyan Zhao; Liwen Qian; Yang Yang; Jing Wu; Leilei Huang; Chunqi Shi; Yuhong Wei; Yue Lu; Ningzi Guan; Haifeng Ye; Jinghong Chen; Runxi Zhang

doi:10.1109/ISSCC49663.2026.11409025

A 48-Day-Duration Pasting Bioelectronic Device Realizing Closed-Loop Realtime Detection and Precision Treatment for Type-1 Diabetes

Xiaoyuan Wu
, Kangjie Zhao
, Mengyao Liu
, Shixiang Ding
, Xuyang Li
, Yuri Lu
, Ruohan Wang
, Ziyan Zhao
, Liwen Qian
, Yang Yang
, Jing Wu
, Leilei Huang^*
, Chunqi Shi^*
, Yuhong Wei
, Yue Lu
, Ningzi Guan
, Haifeng Ye^*
, Jinghong Chen
, Runxi Zhang^*

^*此作品的通讯作者

East China Normal University
University of Houston

科研成果: 书/报告/会议事项章节 › 会议稿件 › 同行评审

摘要

Conventional management of type-1 diabetes (T1D) relies on finger-prick blood sampling or electrochemical methods, which prevent continuous monitoring and treatment. This paper presents a novel epidermal pasting bioelectronic device (PBD). The device integrates a 19fA-resolution bioluminescence analog front-end (BAFE) with TDM-SAR calibration and a hybrid-mode LED driver. It enables closed-loop realtime detection and precision treatment for T1D. The battery life reaches 48 days.

源语言	英语
主期刊名	2026 IEEE International Solid-State Circuits Conference, ISSCC 2026
出版商	Institute of Electrical and Electronics Engineers Inc.
页	498-500
页数	3
ISBN（电子版）	9798331589363
DOI	https://doi.org/10.1109/ISSCC49663.2026.11409025
出版状态	已出版 - 2026
活动	2026 IEEE International Solid-State Circuits Conference, ISSCC 2026 - San Francisco, 美国期限: 15 2月 2026 → 19 2月 2026

出版系列

姓名	Digest of Technical Papers - IEEE International Solid-State Circuits Conference
卷	69
ISSN（印刷版）	0193-6530

会议

会议	2026 IEEE International Solid-State Circuits Conference, ISSCC 2026
国家/地区	美国
市	San Francisco
时期	15/02/26 → 19/02/26

联合国可持续发展目标

此成果有助于实现下列可持续发展目标：

可持续发展目标 3 良好健康与福祉

访问文件

10.1109/ISSCC49663.2026.11409025

其它文件与链接

链接到 Scopus 的出版物

引用此

Wu, X., Zhao, K., Liu, M., Ding, S., Li, X., Lu, Y., Wang, R., Zhao, Z., Qian, L., Yang, Y., Wu, J., Huang, L., Shi, C., Wei, Y., Lu, Y., Guan, N., Ye, H., Chen, J., & Zhang, R. (2026). A 48-Day-Duration Pasting Bioelectronic Device Realizing Closed-Loop Realtime Detection and Precision Treatment for Type-1 Diabetes. 在 2026 IEEE International Solid-State Circuits Conference, ISSCC 2026 (页码 498-500). (Digest of Technical Papers - IEEE International Solid-State Circuits Conference; 卷 69). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/ISSCC49663.2026.11409025

Wu, Xiaoyuan ; Zhao, Kangjie ; Liu, Mengyao 等. / A 48-Day-Duration Pasting Bioelectronic Device Realizing Closed-Loop Realtime Detection and Precision Treatment for Type-1 Diabetes. 2026 IEEE International Solid-State Circuits Conference, ISSCC 2026. Institute of Electrical and Electronics Engineers Inc., 2026. 页码 498-500 (Digest of Technical Papers - IEEE International Solid-State Circuits Conference).

@inproceedings{c334aa83785a4b90b4c317c3556d8102,

title = "A 48-Day-Duration Pasting Bioelectronic Device Realizing Closed-Loop Realtime Detection and Precision Treatment for Type-1 Diabetes",

abstract = "Conventional management of type-1 diabetes (T1D) relies on finger-prick blood sampling or electrochemical methods, which prevent continuous monitoring and treatment. This paper presents a novel epidermal pasting bioelectronic device (PBD). The device integrates a 19fA-resolution bioluminescence analog front-end (BAFE) with TDM-SAR calibration and a hybrid-mode LED driver. It enables closed-loop realtime detection and precision treatment for T1D. The battery life reaches 48 days.",

author = "Xiaoyuan Wu and Kangjie Zhao and Mengyao Liu and Shixiang Ding and Xuyang Li and Yuri Lu and Ruohan Wang and Ziyan Zhao and Liwen Qian and Yang Yang and Jing Wu and Leilei Huang and Chunqi Shi and Yuhong Wei and Yue Lu and Ningzi Guan and Haifeng Ye and Jinghong Chen and Runxi Zhang",

note = "Publisher Copyright: {\textcopyright} 2026 IEEE.; 2026 IEEE International Solid-State Circuits Conference, ISSCC 2026 ; Conference date: 15-02-2026 Through 19-02-2026",

year = "2026",

doi = "10.1109/ISSCC49663.2026.11409025",

language = "英语",

series = "Digest of Technical Papers - IEEE International Solid-State Circuits Conference",

publisher = "Institute of Electrical and Electronics Engineers Inc.",

pages = "498--500",

booktitle = "2026 IEEE International Solid-State Circuits Conference, ISSCC 2026",

address = "美国",

}

Wu, X, Zhao, K, Liu, M, Ding, S, Li, X, Lu, Y, Wang, R, Zhao, Z, Qian, L, Yang, Y, Wu, J, Huang, L, Shi, C, Wei, Y, Lu, Y , Guan, N , Ye, H, Chen, J & Zhang, R 2026, A 48-Day-Duration Pasting Bioelectronic Device Realizing Closed-Loop Realtime Detection and Precision Treatment for Type-1 Diabetes. 在 2026 IEEE International Solid-State Circuits Conference, ISSCC 2026. Digest of Technical Papers - IEEE International Solid-State Circuits Conference, 卷 69, Institute of Electrical and Electronics Engineers Inc., 页码 498-500, 2026 IEEE International Solid-State Circuits Conference, ISSCC 2026, San Francisco, 美国, 15/02/26. https://doi.org/10.1109/ISSCC49663.2026.11409025

A 48-Day-Duration Pasting Bioelectronic Device Realizing Closed-Loop Realtime Detection and Precision Treatment for Type-1 Diabetes. / Wu, Xiaoyuan; Zhao, Kangjie; Liu, Mengyao 等.
2026 IEEE International Solid-State Circuits Conference, ISSCC 2026. Institute of Electrical and Electronics Engineers Inc., 2026. 页码 498-500 (Digest of Technical Papers - IEEE International Solid-State Circuits Conference; 卷 69).

科研成果: 书/报告/会议事项章节 › 会议稿件 › 同行评审

TY - GEN

T1 - A 48-Day-Duration Pasting Bioelectronic Device Realizing Closed-Loop Realtime Detection and Precision Treatment for Type-1 Diabetes

AU - Wu, Xiaoyuan

AU - Zhao, Kangjie

AU - Liu, Mengyao

AU - Ding, Shixiang

AU - Li, Xuyang

AU - Lu, Yuri

AU - Wang, Ruohan

AU - Zhao, Ziyan

AU - Qian, Liwen

AU - Yang, Yang

AU - Wu, Jing

AU - Huang, Leilei

AU - Shi, Chunqi

AU - Wei, Yuhong

AU - Lu, Yue

AU - Guan, Ningzi

AU - Ye, Haifeng

AU - Chen, Jinghong

AU - Zhang, Runxi

PY - 2026

Y1 - 2026

N2 - Conventional management of type-1 diabetes (T1D) relies on finger-prick blood sampling or electrochemical methods, which prevent continuous monitoring and treatment. This paper presents a novel epidermal pasting bioelectronic device (PBD). The device integrates a 19fA-resolution bioluminescence analog front-end (BAFE) with TDM-SAR calibration and a hybrid-mode LED driver. It enables closed-loop realtime detection and precision treatment for T1D. The battery life reaches 48 days.

AB - Conventional management of type-1 diabetes (T1D) relies on finger-prick blood sampling or electrochemical methods, which prevent continuous monitoring and treatment. This paper presents a novel epidermal pasting bioelectronic device (PBD). The device integrates a 19fA-resolution bioluminescence analog front-end (BAFE) with TDM-SAR calibration and a hybrid-mode LED driver. It enables closed-loop realtime detection and precision treatment for T1D. The battery life reaches 48 days.

UR - https://www.scopus.com/pages/publications/105035313374

U2 - 10.1109/ISSCC49663.2026.11409025

DO - 10.1109/ISSCC49663.2026.11409025

M3 - 会议稿件

AN - SCOPUS:105035313374

T3 - Digest of Technical Papers - IEEE International Solid-State Circuits Conference

SP - 498

EP - 500

BT - 2026 IEEE International Solid-State Circuits Conference, ISSCC 2026

PB - Institute of Electrical and Electronics Engineers Inc.

T2 - 2026 IEEE International Solid-State Circuits Conference, ISSCC 2026

Y2 - 15 February 2026 through 19 February 2026

ER -

Wu X, Zhao K, Liu M, Ding S, Li X, Lu Y 等. A 48-Day-Duration Pasting Bioelectronic Device Realizing Closed-Loop Realtime Detection and Precision Treatment for Type-1 Diabetes. 在 2026 IEEE International Solid-State Circuits Conference, ISSCC 2026. Institute of Electrical and Electronics Engineers Inc. 2026. 页码 498-500. (Digest of Technical Papers - IEEE International Solid-State Circuits Conference). doi: 10.1109/ISSCC49663.2026.11409025

A 48-Day-Duration Pasting Bioelectronic Device Realizing Closed-Loop Realtime Detection and Precision Treatment for Type-1 Diabetes

摘要

出版系列

会议

联合国可持续发展目标

访问文件

其它文件与链接

指纹

引用此