Zinc triflate-mediated cyclopropanation of oxindoles with vinyl diphenyl sulfonium triflate: a mild reaction with broad functional group compatibility

Mingwei Zhou; Ke En; Yimin Hu; Yufang Xu; Hong C. Shen; Xuhong Qian

doi:10.1039/C6RA24985J

Zinc triflate-mediated cyclopropanation of oxindoles with vinyl diphenyl sulfonium triflate: a mild reaction with broad functional group compatibility

Mingwei Zhou, Ke En, Yimin Hu, Yufang Xu, Hong C. Shen, Xuhong Qian

Research output: Contribution to journal › Article › peer-review

38 Scopus citations

Abstract

The first use of zinc triflate for the cyclopropanation of unprotected oxindoles with vinyl diphenyl sulfonium triflate salt is reported. The reaction proceeded under ambient conditions and consistently provided high yields with broad functional group tolerability. The utility for the late-stage functionalization (LSF) of complex molecules is demonstrated.

Original language	English
Pages (from-to)	3741-3745
Number of pages	5
Journal	RSC Advances
Volume	7
Issue number	7
DOIs	https://doi.org/10.1039/C6RA24985J
State	Published - 2017
Externally published	Yes

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title = "Zinc triflate-mediated cyclopropanation of oxindoles with vinyl diphenyl sulfonium triflate: a mild reaction with broad functional group compatibility",

abstract = "The first use of zinc triflate for the cyclopropanation of unprotected oxindoles with vinyl diphenyl sulfonium triflate salt is reported. The reaction proceeded under ambient conditions and consistently provided high yields with broad functional group tolerability. The utility for the late-stage functionalization (LSF) of complex molecules is demonstrated.",

author = "Mingwei Zhou and Ke En and Yimin Hu and Yufang Xu and Shen, \{Hong C.\} and Xuhong Qian",

note = "Publisher Copyright: {\textcopyright} The Royal Society of Chemistry.",

year = "2017",

doi = "10.1039/C6RA24985J",

language = "英语",

volume = "7",

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T1 - Zinc triflate-mediated cyclopropanation of oxindoles with vinyl diphenyl sulfonium triflate

T2 - a mild reaction with broad functional group compatibility

AU - Zhou, Mingwei

AU - En, Ke

AU - Hu, Yimin

AU - Xu, Yufang

AU - Shen, Hong C.

AU - Qian, Xuhong

PY - 2017

Y1 - 2017

N2 - The first use of zinc triflate for the cyclopropanation of unprotected oxindoles with vinyl diphenyl sulfonium triflate salt is reported. The reaction proceeded under ambient conditions and consistently provided high yields with broad functional group tolerability. The utility for the late-stage functionalization (LSF) of complex molecules is demonstrated.

AB - The first use of zinc triflate for the cyclopropanation of unprotected oxindoles with vinyl diphenyl sulfonium triflate salt is reported. The reaction proceeded under ambient conditions and consistently provided high yields with broad functional group tolerability. The utility for the late-stage functionalization (LSF) of complex molecules is demonstrated.

UR - https://www.scopus.com/pages/publications/85010383553

U2 - 10.1039/C6RA24985J

DO - 10.1039/C6RA24985J

M3 - 文章

AN - SCOPUS:85010383553

SN - 2046-2069

VL - 7

SP - 3741

EP - 3745

JO - RSC Advances

JF - RSC Advances

IS - 7

ER -

Zinc triflate-mediated cyclopropanation of oxindoles with vinyl diphenyl sulfonium triflate: a mild reaction with broad functional group compatibility

Abstract

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