Ytterbium(III) perfluorooctanoate catalyzed one-pot, three-component synthesis of fully substituted pyrazoles under solvent-free conditions

  • Li Shen
  • , Song Cao*
  • , Nianjin Liu
  • , Jingjing Wu
  • , Longjie Zhu
  • , Xuhong Qian
  • *Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

50 Scopus citations

Abstract

A convenient one-pot synthesis of fully substituted pyrazoles via three-component condensations of phenylhydrazine, aldehydes, and 1,3-dicarbonyl compounds using ytterbium perfluorooctanoate [Yb(PFO)3] as catalyst under solvent-free conditions is described. The reusable catalyst can be easily prepared and was efficient for the reaction. A possible mechanism is suggested.

Original languageEnglish
Pages (from-to)1341-1344
Number of pages4
JournalSynlett
Issue number9
DOIs
StatePublished - 11 May 2008
Externally publishedYes

Keywords

  • Catalyst
  • Pyrazole
  • Solvent-free synthesis
  • Three-component synthesis
  • Yb(PFO)

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