Abstract
A convenient one-pot synthesis of fully substituted pyrazoles via three-component condensations of phenylhydrazine, aldehydes, and 1,3-dicarbonyl compounds using ytterbium perfluorooctanoate [Yb(PFO)3] as catalyst under solvent-free conditions is described. The reusable catalyst can be easily prepared and was efficient for the reaction. A possible mechanism is suggested.
| Original language | English |
|---|---|
| Pages (from-to) | 1341-1344 |
| Number of pages | 4 |
| Journal | Synlett |
| Issue number | 9 |
| DOIs | |
| State | Published - 11 May 2008 |
| Externally published | Yes |
Keywords
- Catalyst
- Pyrazole
- Solvent-free synthesis
- Three-component synthesis
- Yb(PFO)