When SLC46A2 delivers cargo into keratinocytes

Xinxin Wang; Yuping Lai

doi:10.1016/j.immuni.2023.04.008

When SLC46A2 delivers cargo into keratinocytes

Xinxin Wang, Yuping Lai

School of Life Sciences

East China Normal University

Research output: Contribution to journal › Comment/debate

Abstract

How pattern recognition receptors NOD1 and NOD2 sense bacterial muropeptides from extracellular bacteria to drive keratinocyte inflammation remains unclear. In this issue of Immunity, Bharadwaj et al. show that the solute carrier 46A2 (SLC46A2) delivers DAP-muropeptides into the cytosol to drive NOD1 activation in keratinocytes and elicit skin inflammation during psoriasis.

Original language	English
Pages (from-to)	897-900
Number of pages	4
Journal	Immunity
Volume	56
Issue number	5
DOIs	https://doi.org/10.1016/j.immuni.2023.04.008
State	Published - 9 May 2023

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10.1016/j.immuni.2023.04.008

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@article{69815c1e2b764f2eaf0777e074f74881,

title = "When SLC46A2 delivers cargo into keratinocytes",

abstract = "How pattern recognition receptors NOD1 and NOD2 sense bacterial muropeptides from extracellular bacteria to drive keratinocyte inflammation remains unclear. In this issue of Immunity, Bharadwaj et al. show that the solute carrier 46A2 (SLC46A2) delivers DAP-muropeptides into the cytosol to drive NOD1 activation in keratinocytes and elicit skin inflammation during psoriasis.",

author = "Xinxin Wang and Yuping Lai",

note = "Publisher Copyright: {\textcopyright} 2023 Elsevier Inc.",

year = "2023",

month = may,

day = "9",

doi = "10.1016/j.immuni.2023.04.008",

language = "英语",

volume = "56",

pages = "897--900",

journal = "Immunity",

issn = "1074-7613",

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T1 - When SLC46A2 delivers cargo into keratinocytes

AU - Wang, Xinxin

AU - Lai, Yuping

PY - 2023/5/9

Y1 - 2023/5/9

N2 - How pattern recognition receptors NOD1 and NOD2 sense bacterial muropeptides from extracellular bacteria to drive keratinocyte inflammation remains unclear. In this issue of Immunity, Bharadwaj et al. show that the solute carrier 46A2 (SLC46A2) delivers DAP-muropeptides into the cytosol to drive NOD1 activation in keratinocytes and elicit skin inflammation during psoriasis.

AB - How pattern recognition receptors NOD1 and NOD2 sense bacterial muropeptides from extracellular bacteria to drive keratinocyte inflammation remains unclear. In this issue of Immunity, Bharadwaj et al. show that the solute carrier 46A2 (SLC46A2) delivers DAP-muropeptides into the cytosol to drive NOD1 activation in keratinocytes and elicit skin inflammation during psoriasis.

UR - https://www.scopus.com/pages/publications/85154595996

U2 - 10.1016/j.immuni.2023.04.008

DO - 10.1016/j.immuni.2023.04.008

M3 - 评论/辩论

C2 - 37163988

AN - SCOPUS:85154595996

SN - 1074-7613

VL - 56

SP - 897

EP - 900

JO - Immunity

JF - Immunity

IS - 5

ER -

When SLC46A2 delivers cargo into keratinocytes

Abstract

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