Visible-Light-Induced NaI-Catalyzed α-C–H Sulfenylation Enables the Synthesis of o-Sulfanylarylamines

Xiaoming Zhu; Jiahong Li; Zheyu Deng; Jiaolong Meng; Jianxin Tang; Xia He; Yuming Nie; Xinbo Hou; Fuxing Zhang; Xuefeng Jiang

doi:10.1021/acs.orglett.6c01487

Visible-Light-Induced NaI-Catalyzed α-C–H Sulfenylation Enables the Synthesis of o-Sulfanylarylamines

Xiaoming Zhu^*
, Jiahong Li
, Zheyu Deng
, Jiaolong Meng
, Jianxin Tang
, Xia He
, Yuming Nie
, Xinbo Hou
, Fuxing Zhang
, Xuefeng Jiang^*

^*Corresponding author for this work

School of Chemistry and Molecular Engineering

Hengyang Normal University
East China Normal University

Research output: Contribution to journal › Letter › peer-review

Abstract

A novel, atom-economical, and environmentally friendly method for the synthesis of o-sulfanylarylamines from arylamines and diaryl disulfides has been developed by constructing C–S bonds from C–H bonds under visible-light irradiation in the absence of transition metals, additives, and photosensitizers. This reaction exhibited a broad substrate scope and excellent functional group compatibility. Furthermore, the efficiency of the continuous flow process demonstrated the potential of the protocol for practical industrial applications.

Original language	English
Pages (from-to)	6139-6145
Number of pages	7
Journal	Organic Letters
Volume	28
Issue number	19
DOIs	https://doi.org/10.1021/acs.orglett.6c01487
State	Published - 15 May 2026

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title = "Visible-Light-Induced NaI-Catalyzed α-C{\textendash}H Sulfenylation Enables the Synthesis of o-Sulfanylarylamines",

abstract = "A novel, atom-economical, and environmentally friendly method for the synthesis of o-sulfanylarylamines from arylamines and diaryl disulfides has been developed by constructing C{\textendash}S bonds from C{\textendash}H bonds under visible-light irradiation in the absence of transition metals, additives, and photosensitizers. This reaction exhibited a broad substrate scope and excellent functional group compatibility. Furthermore, the efficiency of the continuous flow process demonstrated the potential of the protocol for practical industrial applications.",

author = "Xiaoming Zhu and Jiahong Li and Zheyu Deng and Jiaolong Meng and Jianxin Tang and Xia He and Yuming Nie and Xinbo Hou and Fuxing Zhang and Xuefeng Jiang",

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day = "15",

doi = "10.1021/acs.orglett.6c01487",

language = "英语",

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journal = "Organic Letters",

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TY - JOUR

T1 - Visible-Light-Induced NaI-Catalyzed α-C–H Sulfenylation Enables the Synthesis of o-Sulfanylarylamines

AU - Zhu, Xiaoming

AU - Li, Jiahong

AU - Deng, Zheyu

AU - Meng, Jiaolong

AU - Tang, Jianxin

AU - He, Xia

AU - Nie, Yuming

AU - Hou, Xinbo

AU - Zhang, Fuxing

AU - Jiang, Xuefeng

PY - 2026/5/15

Y1 - 2026/5/15

N2 - A novel, atom-economical, and environmentally friendly method for the synthesis of o-sulfanylarylamines from arylamines and diaryl disulfides has been developed by constructing C–S bonds from C–H bonds under visible-light irradiation in the absence of transition metals, additives, and photosensitizers. This reaction exhibited a broad substrate scope and excellent functional group compatibility. Furthermore, the efficiency of the continuous flow process demonstrated the potential of the protocol for practical industrial applications.

AB - A novel, atom-economical, and environmentally friendly method for the synthesis of o-sulfanylarylamines from arylamines and diaryl disulfides has been developed by constructing C–S bonds from C–H bonds under visible-light irradiation in the absence of transition metals, additives, and photosensitizers. This reaction exhibited a broad substrate scope and excellent functional group compatibility. Furthermore, the efficiency of the continuous flow process demonstrated the potential of the protocol for practical industrial applications.

UR - https://www.scopus.com/pages/publications/105038971996

U2 - 10.1021/acs.orglett.6c01487

DO - 10.1021/acs.orglett.6c01487

M3 - 快报

C2 - 42090475

AN - SCOPUS:105038971996

SN - 1523-7060

VL - 28

SP - 6139

EP - 6145

JO - Organic Letters

JF - Organic Letters

IS - 19

ER -

Visible-Light-Induced NaI-Catalyzed α-C–H Sulfenylation Enables the Synthesis of o-Sulfanylarylamines

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