Ultrasmall NaGdF4 nanodots for efficient MR angiography and atherosclerotic plaque imaging

Huaiyong Xing; Shengjian Zhang; Wenbo Bu; Xiangpeng Zheng; Lijun Wang; Qingfeng Xiao; Dalong Ni; Jiamin Zhang; Liangping Zhou; Weijun Peng; Kuaile Zhao; Yanqing Hua; Jianlin Shi

doi:10.1002/adma.201305222

Ultrasmall NaGdF₄ nanodots for efficient MR angiography and atherosclerotic plaque imaging

Huaiyong Xing
, Shengjian Zhang
, Wenbo Bu^*
, Xiangpeng Zheng
, Lijun Wang
, Qingfeng Xiao
, Dalong Ni
, Jiamin Zhang
, Liangping Zhou
, Weijun Peng
, Kuaile Zhao
, Yanqing Hua
, Jianlin Shi

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

177 Scopus citations

Abstract

Herein, ultrasmall NaGdF₄ nanodots (~2 nm) with DTPA conjugation have been synthesized for efficient MR angiography. Impressively, the r ₁ value in MRI reaches up to 8.93 mM^-1·s ^-1. The ultrasmall vessel lumen of a rabbit is lighted up remarkably. After 3 h, atherosclerotic plaques could be discriminated clearly. This is beneficial for the accurate early diagnosis of vascular pathema.

Original language	English
Pages (from-to)	3867-3872
Number of pages	6
Journal	Advanced Materials
Volume	26
Issue number	23
DOIs	https://doi.org/10.1002/adma.201305222
State	Published - 18 Jun 2014
Externally published	Yes

Keywords

MR
angiography
atherosclerotic plaques
contrast agents

Access to Document

10.1002/adma.201305222

Cite this

@article{0f7b75ce5b174088b7c663c3f088e3a4,

title = "Ultrasmall NaGdF4 nanodots for efficient MR angiography and atherosclerotic plaque imaging",

abstract = "Herein, ultrasmall NaGdF4 nanodots (\textasciitilde{}2 nm) with DTPA conjugation have been synthesized for efficient MR angiography. Impressively, the r 1 value in MRI reaches up to 8.93 mM-1·s -1. The ultrasmall vessel lumen of a rabbit is lighted up remarkably. After 3 h, atherosclerotic plaques could be discriminated clearly. This is beneficial for the accurate early diagnosis of vascular pathema.",

keywords = "MR, angiography, atherosclerotic plaques, contrast agents",

author = "Huaiyong Xing and Shengjian Zhang and Wenbo Bu and Xiangpeng Zheng and Lijun Wang and Qingfeng Xiao and Dalong Ni and Jiamin Zhang and Liangping Zhou and Weijun Peng and Kuaile Zhao and Yanqing Hua and Jianlin Shi",

year = "2014",

month = jun,

day = "18",

doi = "10.1002/adma.201305222",

language = "英语",

volume = "26",

pages = "3867--3872",

journal = "Advanced Materials",

issn = "0935-9648",

publisher = "Wiley-Blackwell",

number = "23",

}

TY - JOUR

T1 - Ultrasmall NaGdF4 nanodots for efficient MR angiography and atherosclerotic plaque imaging

AU - Xing, Huaiyong

AU - Zhang, Shengjian

AU - Bu, Wenbo

AU - Zheng, Xiangpeng

AU - Wang, Lijun

AU - Xiao, Qingfeng

AU - Ni, Dalong

AU - Zhang, Jiamin

AU - Zhou, Liangping

AU - Peng, Weijun

AU - Zhao, Kuaile

AU - Hua, Yanqing

AU - Shi, Jianlin

PY - 2014/6/18

Y1 - 2014/6/18

N2 - Herein, ultrasmall NaGdF4 nanodots (~2 nm) with DTPA conjugation have been synthesized for efficient MR angiography. Impressively, the r 1 value in MRI reaches up to 8.93 mM-1·s -1. The ultrasmall vessel lumen of a rabbit is lighted up remarkably. After 3 h, atherosclerotic plaques could be discriminated clearly. This is beneficial for the accurate early diagnosis of vascular pathema.

AB - Herein, ultrasmall NaGdF4 nanodots (~2 nm) with DTPA conjugation have been synthesized for efficient MR angiography. Impressively, the r 1 value in MRI reaches up to 8.93 mM-1·s -1. The ultrasmall vessel lumen of a rabbit is lighted up remarkably. After 3 h, atherosclerotic plaques could be discriminated clearly. This is beneficial for the accurate early diagnosis of vascular pathema.

KW - MR

KW - angiography

KW - atherosclerotic plaques

KW - contrast agents

UR - https://www.scopus.com/pages/publications/84902385302

U2 - 10.1002/adma.201305222

DO - 10.1002/adma.201305222

M3 - 文章

C2 - 24677351

AN - SCOPUS:84902385302

SN - 0935-9648

VL - 26

SP - 3867

EP - 3872

JO - Advanced Materials

JF - Advanced Materials

IS - 23

ER -

Ultrasmall NaGdF₄ nanodots for efficient MR angiography and atherosclerotic plaque imaging

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this