@inproceedings{a0df50240cb6442fa83ce65df575959d,
title = "Ultrasensitive electrical detection of hepatitis b virus using silicon nanowire sensor",
abstract = "Herein, we describe a novel approach for rapid, label-free and ultrasensitive detection of Hepatitis B virus (HBV) DNA by applying rolling circle amplification (RCA) based on silicon nanowire field-effect transistor (SiNW-FET). Optical lithography and anisotropic self-stop etching were employed to guarantee low cost batch production for SiNWs. The RCA reaction created a long single-stranded DNA (ssDNA) product and thus enhanced the electronic responses of SiNW significantly. The ultrahigh sensitivity for 1 fM HBV DNA detection and high specificity for single-nucleotide polymorphism discrimination were achieved.",
keywords = "CMOS-compatible, Nanosensor, RCA, Silicon nanowire",
author = "Anran Gao and Na Lu and Pengfei Dai and Tie Li and Yuelin Wang",
note = "Publisher Copyright: {\textcopyright} 14CBMS.; 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 ; Conference date: 26-10-2014 Through 30-10-2014",
year = "2014",
language = "英语",
series = "18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014",
publisher = "Chemical and Biological Microsystems Society",
pages = "2008--2010",
booktitle = "18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014",
}
