Total synthesis of (±)-galanthamine

Xiang Dong Hu; Yong Qiang Tu; En Zhang; Shuanhu Gao; Shaohua Wang; Aixia Wang; Chun An Fan; Min Wang

doi:10.1021/ol060339b

Total synthesis of (±)-galanthamine

Xiang Dong Hu
, Yong Qiang Tu^*
, En Zhang
, Shuanhu Gao
, Shaohua Wang
, Aixia Wang
, Chun An Fan
, Min Wang

^*Corresponding author for this work

Lanzhou University

Research output: Contribution to journal › Article › peer-review

77 Scopus citations

Abstract

A practical and efficient total synthesis of (±)-galanthamine was achieved from commercially available materials through a novel approach, in which the construction of its core structure and the special allylic group were based on a successive semipinacol rearrangement/desilyation/cyclization and Saegusa-Ito oxidation, respectively.

Original language	English
Pages (from-to)	1823-1825
Number of pages	3
Journal	Organic Letters
Volume	8
Issue number	9
DOIs	https://doi.org/10.1021/ol060339b
State	Published - 27 Apr 2006
Externally published	Yes

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10.1021/ol060339b

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title = "Total synthesis of (±)-galanthamine",

abstract = "A practical and efficient total synthesis of (±)-galanthamine was achieved from commercially available materials through a novel approach, in which the construction of its core structure and the special allylic group were based on a successive semipinacol rearrangement/desilyation/cyclization and Saegusa-Ito oxidation, respectively.",

author = "Hu, \{Xiang Dong\} and Tu, \{Yong Qiang\} and En Zhang and Shuanhu Gao and Shaohua Wang and Aixia Wang and Fan, \{Chun An\} and Min Wang",

year = "2006",

month = apr,

day = "27",

doi = "10.1021/ol060339b",

language = "英语",

volume = "8",

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journal = "Organic Letters",

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T1 - Total synthesis of (±)-galanthamine

AU - Hu, Xiang Dong

AU - Tu, Yong Qiang

AU - Zhang, En

AU - Gao, Shuanhu

AU - Wang, Shaohua

AU - Wang, Aixia

AU - Fan, Chun An

AU - Wang, Min

PY - 2006/4/27

Y1 - 2006/4/27

N2 - A practical and efficient total synthesis of (±)-galanthamine was achieved from commercially available materials through a novel approach, in which the construction of its core structure and the special allylic group were based on a successive semipinacol rearrangement/desilyation/cyclization and Saegusa-Ito oxidation, respectively.

AB - A practical and efficient total synthesis of (±)-galanthamine was achieved from commercially available materials through a novel approach, in which the construction of its core structure and the special allylic group were based on a successive semipinacol rearrangement/desilyation/cyclization and Saegusa-Ito oxidation, respectively.

UR - https://www.scopus.com/pages/publications/33646456628

U2 - 10.1021/ol060339b

DO - 10.1021/ol060339b

M3 - 文章

C2 - 16623560

AN - SCOPUS:33646456628

SN - 1523-7060

VL - 8

SP - 1823

EP - 1825

JO - Organic Letters

JF - Organic Letters

IS - 9

ER -

Total synthesis of (±)-galanthamine

Abstract

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