Total synthesis of cyanthiwigins A, C, G, and H

Cheng Wang; Dan Wang; Shuanhu Gao

doi:10.1021/ol4019425

Total synthesis of cyanthiwigins A, C, G, and H

Cheng Wang
, Dan Wang
, Shuanhu Gao^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

33 Scopus citations

Abstract

The first total synthesis of cyanthiwigins A, C, H and concise synthesis of cyanthiwigin G was achieved from a common intermediate. A modified formal [4 + 2] cycloaddition was developed to construct the key cis-hydrindanone (A-B). Stereospecific 1,4-addition, alkylation, and ring-closing metathesis were used to build the tricarbocyclic ring system (A-B-C). Various site-selective oxidations were applied to create the desired oxidation states of the different cyanthiwigins.

Original language	English
Pages (from-to)	4402-4405
Number of pages	4
Journal	Organic Letters
Volume	15
Issue number	17
DOIs	https://doi.org/10.1021/ol4019425
State	Published - 6 Sep 2013
Externally published	Yes

Access to Document

10.1021/ol4019425

Cite this

@article{b1db0606f2294020bf5f503872d578c7,

title = "Total synthesis of cyanthiwigins A, C, G, and H",

abstract = "The first total synthesis of cyanthiwigins A, C, H and concise synthesis of cyanthiwigin G was achieved from a common intermediate. A modified formal [4 + 2] cycloaddition was developed to construct the key cis-hydrindanone (A-B). Stereospecific 1,4-addition, alkylation, and ring-closing metathesis were used to build the tricarbocyclic ring system (A-B-C). Various site-selective oxidations were applied to create the desired oxidation states of the different cyanthiwigins.",

author = "Cheng Wang and Dan Wang and Shuanhu Gao",

year = "2013",

month = sep,

day = "6",

doi = "10.1021/ol4019425",

language = "英语",

volume = "15",

pages = "4402--4405",

journal = "Organic Letters",

issn = "1523-7060",

publisher = "American Chemical Society",

number = "17",

}

TY - JOUR

T1 - Total synthesis of cyanthiwigins A, C, G, and H

AU - Wang, Cheng

AU - Wang, Dan

AU - Gao, Shuanhu

PY - 2013/9/6

Y1 - 2013/9/6

N2 - The first total synthesis of cyanthiwigins A, C, H and concise synthesis of cyanthiwigin G was achieved from a common intermediate. A modified formal [4 + 2] cycloaddition was developed to construct the key cis-hydrindanone (A-B). Stereospecific 1,4-addition, alkylation, and ring-closing metathesis were used to build the tricarbocyclic ring system (A-B-C). Various site-selective oxidations were applied to create the desired oxidation states of the different cyanthiwigins.

AB - The first total synthesis of cyanthiwigins A, C, H and concise synthesis of cyanthiwigin G was achieved from a common intermediate. A modified formal [4 + 2] cycloaddition was developed to construct the key cis-hydrindanone (A-B). Stereospecific 1,4-addition, alkylation, and ring-closing metathesis were used to build the tricarbocyclic ring system (A-B-C). Various site-selective oxidations were applied to create the desired oxidation states of the different cyanthiwigins.

UR - https://www.scopus.com/pages/publications/84883824626

U2 - 10.1021/ol4019425

DO - 10.1021/ol4019425

M3 - 文章

C2 - 23947478

AN - SCOPUS:84883824626

SN - 1523-7060

VL - 15

SP - 4402

EP - 4405

JO - Organic Letters

JF - Organic Letters

IS - 17

ER -

Total synthesis of cyanthiwigins A, C, G, and H

Abstract

Access to Document

Other files and links

Fingerprint

Cite this