TY - JOUR
T1 - Topotactic Conversion of Copper(I) Phosphide Nanowires for Sensitive Electrochemical Detection of H2O2 Release from Living Cells
AU - Li, Zhenzhen
AU - Xin, Yanmei
AU - Wu, Wenlong
AU - Fu, Baihe
AU - Zhang, Zhonghai
N1 - Publisher Copyright:
© 2016 American Chemical Society.
PY - 2016/8/2
Y1 - 2016/8/2
N2 - In this work, we clearly demonstrate for the first time the use of transition-metal phosphides to set up a new cathodic analysis platform for sensitive and selective electrochemical nonenzymatic detection of H2O2. With the help of a facile topotactic conversion method, the noble metal-free electrocatalyst of copper(I) phosphide nanowires on three-dimensional porous copper foam (Cu3P NWs/CF) is fabricated with electrochemical anodized Cu(OH)2 NWs as precursor. The Cu3P NWs/CF-based sensor presents excellent electrocatalytic activity for H2O2 reduction with a detection limit of 2 nM, the lowest detection limit achieved by noble-metal free electrocatalyst, which guarantees the possibility of sensitive and reliable detection of H2O2 release from living tumorigenic cells, thus showing the potential application as a sensitive cancer cell detection probe.
AB - In this work, we clearly demonstrate for the first time the use of transition-metal phosphides to set up a new cathodic analysis platform for sensitive and selective electrochemical nonenzymatic detection of H2O2. With the help of a facile topotactic conversion method, the noble metal-free electrocatalyst of copper(I) phosphide nanowires on three-dimensional porous copper foam (Cu3P NWs/CF) is fabricated with electrochemical anodized Cu(OH)2 NWs as precursor. The Cu3P NWs/CF-based sensor presents excellent electrocatalytic activity for H2O2 reduction with a detection limit of 2 nM, the lowest detection limit achieved by noble-metal free electrocatalyst, which guarantees the possibility of sensitive and reliable detection of H2O2 release from living tumorigenic cells, thus showing the potential application as a sensitive cancer cell detection probe.
UR - https://www.scopus.com/pages/publications/84982702327
U2 - 10.1021/acs.analchem.6b01637
DO - 10.1021/acs.analchem.6b01637
M3 - 文章
C2 - 27377605
AN - SCOPUS:84982702327
SN - 0003-2700
VL - 88
SP - 7724
EP - 7729
JO - Analytical Chemistry
JF - Analytical Chemistry
IS - 15
ER -
