TY - JOUR
T1 - The rise of ADP-ribose–ubiquitin
AU - Chatrin, Chatrin
AU - Zhu, Kang
AU - Ahel, Ivan
N1 - Publisher Copyright:
© Springer Nature America, Inc. 2025.
PY - 2025/9
Y1 - 2025/9
N2 - Post-translational modifications show mechanistic crosstalk, exemplified by the ADP-ribose–ubiquitin hybrid signal, in which one post-translational modification modifies another. This Comment highlights its discovery, mechanistic basis and functional consequences, and outlines critical questions for understanding this emerging signaling paradigm.
AB - Post-translational modifications show mechanistic crosstalk, exemplified by the ADP-ribose–ubiquitin hybrid signal, in which one post-translational modification modifies another. This Comment highlights its discovery, mechanistic basis and functional consequences, and outlines critical questions for understanding this emerging signaling paradigm.
UR - https://www.scopus.com/pages/publications/105015377328
U2 - 10.1038/s41594-025-01651-0
DO - 10.1038/s41594-025-01651-0
M3 - 评论/辩论
C2 - 40921856
AN - SCOPUS:105015377328
SN - 1545-9993
VL - 32
SP - 1582
EP - 1585
JO - Nature Structural and Molecular Biology
JF - Nature Structural and Molecular Biology
IS - 9
ER -