The first catalytic asymmetric thioacetalization by chiral phosphoric acid catalysis

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Abstract

We report here the first catalytic asymmetric thioacetalization of salicylaldehyde and dithiol. Chiral phosphoric acid STRIP C5 is identified as a powerful catalyst for this reaction to afford various chiral dithioacetals in high to excellent yields and enantioselectivities under mild conditions.

Original languageEnglish
Pages (from-to)2205-2209
Number of pages5
JournalOrganic and Biomolecular Chemistry
Volume14
Issue number7
DOIs
StatePublished - 21 Feb 2016

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