The first catalytic asymmetric morita-baylis-hillman reaction of acrolein with aromatic aldehydes

Xingping Zeng; Yunlin Liu; Congbin Ji; Jian Zhou

doi:10.1002/cjoc.201200937

The first catalytic asymmetric morita-baylis-hillman reaction of acrolein with aromatic aldehydes

Xingping Zeng, Yunlin Liu, Congbin Ji, Jian Zhou

School of Chemistry and Molecular Engineering

East China Normal University

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Abstract

We report the first example of catalytic asymmetric Morita-Baylis-Hillman reaction of acrolein with aromatic aldehydes. The use of 10 mol% of Hatakeyama's catalyst β-isocupreidine C4, in combination with 20 mol% of 2,6-dimethoxybenzoic acid, could catalyze the reaction to give the desired products in up to 81% ee.

Original language	English
Pages (from-to)	2631-2635
Number of pages	5
Journal	Chinese Journal of Chemistry
Volume	30
Issue number	11
DOIs	https://doi.org/10.1002/cjoc.201200937
State	Published - Nov 2012

Keywords

2,6-dimethoxybenzoic acid
Morita-Baylis-Hillman reaction
acrolein
organocatalysis
β-isocupreidine

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10.1002/cjoc.201200937

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title = "The first catalytic asymmetric morita-baylis-hillman reaction of acrolein with aromatic aldehydes",

abstract = "We report the first example of catalytic asymmetric Morita-Baylis-Hillman reaction of acrolein with aromatic aldehydes. The use of 10 mol\% of Hatakeyama's catalyst β-isocupreidine C4, in combination with 20 mol\% of 2,6-dimethoxybenzoic acid, could catalyze the reaction to give the desired products in up to 81\% ee.",

keywords = "2,6-dimethoxybenzoic acid, Morita-Baylis-Hillman reaction, acrolein, organocatalysis, β-isocupreidine",

author = "Xingping Zeng and Yunlin Liu and Congbin Ji and Jian Zhou",

year = "2012",

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volume = "30",

pages = "2631--2635",

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T1 - The first catalytic asymmetric morita-baylis-hillman reaction of acrolein with aromatic aldehydes

AU - Zeng, Xingping

AU - Liu, Yunlin

AU - Ji, Congbin

AU - Zhou, Jian

PY - 2012/11

Y1 - 2012/11

N2 - We report the first example of catalytic asymmetric Morita-Baylis-Hillman reaction of acrolein with aromatic aldehydes. The use of 10 mol% of Hatakeyama's catalyst β-isocupreidine C4, in combination with 20 mol% of 2,6-dimethoxybenzoic acid, could catalyze the reaction to give the desired products in up to 81% ee.

AB - We report the first example of catalytic asymmetric Morita-Baylis-Hillman reaction of acrolein with aromatic aldehydes. The use of 10 mol% of Hatakeyama's catalyst β-isocupreidine C4, in combination with 20 mol% of 2,6-dimethoxybenzoic acid, could catalyze the reaction to give the desired products in up to 81% ee.

KW - 2,6-dimethoxybenzoic acid

KW - Morita-Baylis-Hillman reaction

KW - acrolein

KW - organocatalysis

KW - β-isocupreidine

UR - https://www.scopus.com/pages/publications/84869420213

U2 - 10.1002/cjoc.201200937

DO - 10.1002/cjoc.201200937

M3 - 文章

AN - SCOPUS:84869420213

SN - 1001-604X

VL - 30

SP - 2631

EP - 2635

JO - Chinese Journal of Chemistry

JF - Chinese Journal of Chemistry

IS - 11

ER -

The first catalytic asymmetric morita-baylis-hillman reaction of acrolein with aromatic aldehydes

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Keywords

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