The complete genome sequence of a high pristinamycin-producing strain Streptomyces pristinaespiralis HCCB10218

  • Jinzhong Tian
  • , Junjie Yang
  • , Lei Li
  • , Lijun Ruan
  • , Wei Wei
  • , Guosong Zheng
  • , Wei Zhao
  • , Jun Chen
  • , Weihong Jiang
  • , Mei Ge*
  • , Yinhua Lu
  • *Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

Streptomyces pristinaespiralis produces the streptogramin-like antibiotic pristinamycin, which is a mixture of two structurally different components: pristinamycin I (PI) and pristinamycin II (PII). Herein, we report the complete genome sequence of a high pristinamycin-producing strain HCCB10218 (8.5. Mb) obtained by using PacBio RSII combined with Illumina HiSeq 2500 sequencing system. The genome sequence presented here provides clues for the mechanism underlying the higher pristinamycin production of HCCB10218.

Original languageEnglish
Pages (from-to)45-46
Number of pages2
JournalJournal of Biotechnology
Volume214
DOIs
StatePublished - 20 Nov 2015
Externally publishedYes

Keywords

  • Genome sequence
  • Pristinamycin
  • Streptomyces pristinaespiralis

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