Synthetic progress of Fusarisetin A

Jun Yin; Lili Kong; Shuanhu Gao

doi:10.6023/cjoc201210027

Synthetic progress of Fusarisetin A

Jun Yin
, Lili Kong
, Shuanhu Gao^*

^*Corresponding author for this work

School of Chemistry and Molecular Engineering

East China Normal University

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

Fusarisetin A, a new tetramic acid type natural product, contains a 6-6-5-5-5 fused pentacycles and ten stereocenters. Fusarisetin A displays significant inhibition of acinar morphogenesis as well as cell migration and invasion, and shows the potency for selective inhibition of cancer cell metastasis. This review summarizes the synthetic progress of fusarisetin A since its discovery.

Original language	English
Pages (from-to)	259-266
Number of pages	8
Journal	Chinese Journal of Organic Chemistry
Volume	33
Issue number	2
DOIs	https://doi.org/10.6023/cjoc201210027
State	Published - Feb 2013

Keywords

Antitumor
Fusarisetin A
Tetramic acid
Total synthesis
Tumor-cell migration

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.6023/cjoc201210027

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title = "Synthetic progress of Fusarisetin A",

abstract = "Fusarisetin A, a new tetramic acid type natural product, contains a 6-6-5-5-5 fused pentacycles and ten stereocenters. Fusarisetin A displays significant inhibition of acinar morphogenesis as well as cell migration and invasion, and shows the potency for selective inhibition of cancer cell metastasis. This review summarizes the synthetic progress of fusarisetin A since its discovery.",

keywords = "Antitumor, Fusarisetin A, Tetramic acid, Total synthesis, Tumor-cell migration",

author = "Jun Yin and Lili Kong and Shuanhu Gao",

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doi = "10.6023/cjoc201210027",

language = "英语",

volume = "33",

pages = "259--266",

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T1 - Synthetic progress of Fusarisetin A

AU - Yin, Jun

AU - Kong, Lili

AU - Gao, Shuanhu

PY - 2013/2

Y1 - 2013/2

N2 - Fusarisetin A, a new tetramic acid type natural product, contains a 6-6-5-5-5 fused pentacycles and ten stereocenters. Fusarisetin A displays significant inhibition of acinar morphogenesis as well as cell migration and invasion, and shows the potency for selective inhibition of cancer cell metastasis. This review summarizes the synthetic progress of fusarisetin A since its discovery.

AB - Fusarisetin A, a new tetramic acid type natural product, contains a 6-6-5-5-5 fused pentacycles and ten stereocenters. Fusarisetin A displays significant inhibition of acinar morphogenesis as well as cell migration and invasion, and shows the potency for selective inhibition of cancer cell metastasis. This review summarizes the synthetic progress of fusarisetin A since its discovery.

KW - Antitumor

KW - Fusarisetin A

KW - Tetramic acid

KW - Total synthesis

KW - Tumor-cell migration

UR - https://www.scopus.com/pages/publications/84876343406

U2 - 10.6023/cjoc201210027

DO - 10.6023/cjoc201210027

M3 - 文章

AN - SCOPUS:84876343406

SN - 0253-2786

VL - 33

SP - 259

EP - 266

JO - Chinese Journal of Organic Chemistry

JF - Chinese Journal of Organic Chemistry

IS - 2

ER -

Synthetic progress of Fusarisetin A

Abstract

Keywords

UN SDGs

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