Synthesis of the (3R, 9S, 10S)- Diastereoisomer of Panaxytriol, a Potent Antitumor Polyacetylene from Panax ginseng

Wei Lu; Guang Rong Zheng; Jing Shan Shen; Jun Chao Cai

Synthesis of the (3R, 9S, 10S)- Diastereoisomer of Panaxytriol, a Potent Antitumor Polyacetylene from Panax ginseng

Wei Lu
, Guang Rong Zheng
, Jing Shan Shen
, Jun Chao Cai^*

^*Corresponding author for this work

CAS - Shanghai Institute of Materia Medica

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

(3R, 9S, 10S)-Heptadec-1-ene-4,6-diyne-3, 9, 10-triol 2, a diastereoisomer of panaxytriol 1 was synthesized using L-(+)-diethyl tartrate 5 as a chiral template, through the Cadiot-Chodkiczwicz coupling of the terminal acetylene 3 with bromoacetylene 4.

Original language	English
Pages (from-to)	201-204
Number of pages	4
Journal	Chinese Chemical Letters
Volume	10
Issue number	3
State	Published - Mar 1999
Externally published	Yes

Keywords

Cadiot-Chodkiczwicz coupling
Diastereoisomer
Panaxytriol

Cite this

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title = "Synthesis of the (3R, 9S, 10S)- Diastereoisomer of Panaxytriol, a Potent Antitumor Polyacetylene from Panax ginseng",

abstract = "(3R, 9S, 10S)-Heptadec-1-ene-4,6-diyne-3, 9, 10-triol 2, a diastereoisomer of panaxytriol 1 was synthesized using L-(+)-diethyl tartrate 5 as a chiral template, through the Cadiot-Chodkiczwicz coupling of the terminal acetylene 3 with bromoacetylene 4.",

keywords = "Cadiot-Chodkiczwicz coupling, Diastereoisomer, Panaxytriol",

author = "Wei Lu and Zheng, \{Guang Rong\} and Shen, \{Jing Shan\} and Cai, \{Jun Chao\}",

year = "1999",

month = mar,

language = "英语",

volume = "10",

pages = "201--204",

journal = "Chinese Chemical Letters",

issn = "1001-8417",

publisher = "Elsevier B.V.",

number = "3",

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TY - JOUR

T1 - Synthesis of the (3R, 9S, 10S)- Diastereoisomer of Panaxytriol, a Potent Antitumor Polyacetylene from Panax ginseng

AU - Lu, Wei

AU - Zheng, Guang Rong

AU - Shen, Jing Shan

AU - Cai, Jun Chao

PY - 1999/3

Y1 - 1999/3

N2 - (3R, 9S, 10S)-Heptadec-1-ene-4,6-diyne-3, 9, 10-triol 2, a diastereoisomer of panaxytriol 1 was synthesized using L-(+)-diethyl tartrate 5 as a chiral template, through the Cadiot-Chodkiczwicz coupling of the terminal acetylene 3 with bromoacetylene 4.

AB - (3R, 9S, 10S)-Heptadec-1-ene-4,6-diyne-3, 9, 10-triol 2, a diastereoisomer of panaxytriol 1 was synthesized using L-(+)-diethyl tartrate 5 as a chiral template, through the Cadiot-Chodkiczwicz coupling of the terminal acetylene 3 with bromoacetylene 4.

KW - Cadiot-Chodkiczwicz coupling

KW - Diastereoisomer

KW - Panaxytriol

UR - https://www.scopus.com/pages/publications/0033469591

M3 - 文章

AN - SCOPUS:0033469591

SN - 1001-8417

VL - 10

SP - 201

EP - 204

JO - Chinese Chemical Letters

JF - Chinese Chemical Letters

IS - 3

ER -

Synthesis of the (3R, 9S, 10S)- Diastereoisomer of Panaxytriol, a Potent Antitumor Polyacetylene from Panax ginseng

Abstract

Keywords

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