Synthesis of 9-allyl-10-hydroxycamptothecin via Suzuki reaction

Yu Luo; Shanbao Yu; Qingqing Huang; Wei Lu

doi:10.1002/jhet.1549

Synthesis of 9-allyl-10-hydroxycamptothecin via Suzuki reaction

Yu Luo
, Shanbao Yu
, Qingqing Huang
, Wei Lu

School of Chemistry and Molecular Engineering

East China Normal University

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

A facile and eco-friendly approach for synthesizing 9-allyl-10- hydroxycamptothecin (2), a key intermediate for the preparation of camptothecin analogs, is described. The product was obtained in good yield and high purity (≥99% HPLC) under mild Suzuki reaction condition.

Original language	English
Pages (from-to)	1133-1136
Number of pages	4
Journal	Journal of Heterocyclic Chemistry
Volume	51
Issue number	4
DOIs	https://doi.org/10.1002/jhet.1549
State	Published - Jul 2014

Access to Document

10.1002/jhet.1549

Cite this

@article{1d90ca91ec9144f5be78f6d05b796702,

title = "Synthesis of 9-allyl-10-hydroxycamptothecin via Suzuki reaction",

abstract = "A facile and eco-friendly approach for synthesizing 9-allyl-10- hydroxycamptothecin (2), a key intermediate for the preparation of camptothecin analogs, is described. The product was obtained in good yield and high purity (≥99\% HPLC) under mild Suzuki reaction condition.",

author = "Yu Luo and Shanbao Yu and Qingqing Huang and Wei Lu",

year = "2014",

month = jul,

doi = "10.1002/jhet.1549",

language = "英语",

volume = "51",

pages = "1133--1136",

journal = "Journal of Heterocyclic Chemistry",

issn = "0022-152X",

publisher = "John Wiley and Sons Inc",

number = "4",

}

TY - JOUR

T1 - Synthesis of 9-allyl-10-hydroxycamptothecin via Suzuki reaction

AU - Luo, Yu

AU - Yu, Shanbao

AU - Huang, Qingqing

AU - Lu, Wei

PY - 2014/7

Y1 - 2014/7

N2 - A facile and eco-friendly approach for synthesizing 9-allyl-10- hydroxycamptothecin (2), a key intermediate for the preparation of camptothecin analogs, is described. The product was obtained in good yield and high purity (≥99% HPLC) under mild Suzuki reaction condition.

AB - A facile and eco-friendly approach for synthesizing 9-allyl-10- hydroxycamptothecin (2), a key intermediate for the preparation of camptothecin analogs, is described. The product was obtained in good yield and high purity (≥99% HPLC) under mild Suzuki reaction condition.

UR - https://www.scopus.com/pages/publications/84905005203

U2 - 10.1002/jhet.1549

DO - 10.1002/jhet.1549

M3 - 文章

AN - SCOPUS:84905005203

SN - 0022-152X

VL - 51

SP - 1133

EP - 1136

JO - Journal of Heterocyclic Chemistry

JF - Journal of Heterocyclic Chemistry

IS - 4

ER -

Synthesis of 9-allyl-10-hydroxycamptothecin via Suzuki reaction

Abstract

Access to Document

Other files and links

Fingerprint

Cite this