Abstract
Two novel angular thienonaphthopyrones 6 and 8 were synthesized starting from 2,7-naphthalenediol in six steps, respectively. The crystal structure of 6 was determined. The planarity of 6 and the geometry of the active double bond between the α-pyrone and the thieno moieties of 6 suggest that thienonaphthopyrones might be useful as efficient monofunctional DNA intercalators.
| Original language | English |
|---|---|
| Pages (from-to) | 338-343 |
| Number of pages | 6 |
| Journal | Chinese Journal of Organic Chemistry |
| Volume | 20 |
| Issue number | 3 |
| State | Published - 2000 |
| Externally published | Yes |
Keywords
- Characterization
- Synthesis
- Thienonaphthopyrone
- X-ray crystal structure