Synthesis and biological activities of N-(1,2,4-triazole-4-yl)-N′- (fluorine-containing-phenyl)carbamimidothioates

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Abstract

A series of N-(1,2,4-triazole-4-yl)-N-pm-(fluorine-containing-phenyl) carbamimidothioates 5a-i were synthesized by reacting 4-amine-1,2,4-trizaole with corresponding aryl isothiocyanates in ethanol at room temperature and, in a subsequent step, with methyl iodide. The antifungal activities of the title compounds against the fungi Rhizoctonia solan and Pyricularia orizae were screened.

Original languageEnglish
Pages (from-to)79-82
Number of pages4
JournalJournal of Fluorine Chemistry
Volume115
Issue number1
DOIs
StatePublished - 2002
Externally publishedYes

Keywords

  • Biological activity
  • N-(1,2,4-Triazole-4-yl)-N′ -(flourine-containing-phenyl)carbamimidothioates
  • Synthesis

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