Synthesis and biological activities of hydroxyl-protected fluorine-containing 4,4-dihydroxylmethyl-2-aryl-iminothiazolidines

Chuanxiang Liu, Xiaoyong Xu, Zhong Li, Weidong Chen, Qingchun Huang, Xuhong Qian

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

Eight novel compounds were synthesized by a facile and mild method with high yields, and the structures of all the compounds were characterized by 1H NMR IR mass and high resolution mass spectroscopy. Their inhibitory activity against insect-flight and trehalase in vitro were screened. Some target compounds have moderate inhibitory activity against trehalase, and show inhibition action to insect-flight.

Original languageEnglish
Pages (from-to)53-58
Number of pages6
JournalJournal of Fluorine Chemistry
Volume126
Issue number1
DOIs
StatePublished - Jan 2005
Externally publishedYes

Keywords

  • Insect-flight
  • Synthesis
  • Trehalase inhibitors

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