Abstract
A series of novel symmetrical and asymmetrical 2,5-disubstituted-1,3,4-oxadiazoles and their intermediates were synthesized. A convenient procedure for preparation of aromatic nitrile and ester intermediates is reported. The insecticidal activities of oxadiazoles against Dropsophila melanogaster were recorded, and analysis of structure-activity relationships showed that the highest occupied molecular orbital energy (E(H)) was the main factor to affect the bioactivities.
| Original language | English |
|---|---|
| Pages (from-to) | 124-130 |
| Number of pages | 7 |
| Journal | Journal of Chemical Technology and Biotechnology |
| Volume | 67 |
| Issue number | 2 |
| DOIs | |
| State | Published - Oct 1996 |
| Externally published | Yes |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 7 Affordable and Clean Energy
Keywords
- Insecticidal activity
- Organic fluorides
- Oxadiazole
- Structure-activity relationship
- Synthesis
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