Syntheses and effectiveness of functional peptide-based RAFT agents

  • Chao Chen
  • , Fanxing Kong
  • , Xiaohu Wei
  • , San H. Thang*
  • *Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

18 Scopus citations

Abstract

In this study, a series of functional peptide-based RAFT agents were designed and synthesized by the solid-phase supported peptide synthesis method. These novel RAFT agents have enabled chemists to make well-defined peptide-polymer conjugates with complicated topological structures. Additionally, our results have shown an unexpected reaction that takes place during these syntheses, and the conversion of a nitrile group to a carboxamide group has been evidently elucidated and unambiguously confirmed.

Original languageEnglish
Pages (from-to)10776-10779
Number of pages4
JournalChemical Communications
Volume53
Issue number78
DOIs
StatePublished - 2017
Externally publishedYes

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