Syndrome discrimination model of traditional Chinese medicine for chronic hepatitis B

  • Xiaoyu Chen*
  • , Na Chu
  • , Lizhuang Ma
  • , Yiyang Hu
  • *Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Traditional Chinese medicine (TCM) has been widely applied in chronic hepatitis B (CHB), and syndrome discrimination is the most important step of TCM and it is performed subjectively and generally by physicians at present, which hinders the application prospects of TCM. In this paper, a CHB discrimination model of TCM is proposed basing on information gain, logistic attribute selection and space vector, through the approach, critical weighting attributes are selected, and cases are discriminated. The discriminant model is evaluated by CHB dataset, 34 critical weighting attributes are selected and 555 typical cases of two syndromes are identified respectively. And the selected critical attributes are in sound agreement with those used in TCM syndrome differentiation by physicians. Finally, results of this discriminant model for CHB are compared with other methods, and experimental results also show the discriminant model performs well in the application for TCM syndrome differentiation of CHB.

Original languageEnglish
Title of host publicationProceedings - 2012 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2012
Pages310-315
Number of pages6
DOIs
StatePublished - 2012
Externally publishedYes
Event2012 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2012 - Philadelphia, PA, United States
Duration: 4 Oct 20127 Oct 2012

Publication series

NameProceedings - 2012 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2012

Conference

Conference2012 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2012
Country/TerritoryUnited States
CityPhiladelphia, PA
Period4/10/127/10/12

Keywords

  • CHB discriminant model of TCM
  • attribute selection
  • information gain
  • multidimensional vector space

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