Superresolution imaging of DNA tetrahedral nanostructures in cells by STED method with continuous wave lasers

Jiancong Du; Suhui Deng; Shangguo Hou; Lingling Qiao; Jianfang Chen; Qing Huang; Chunhai Fan; Ya Cheng; Yun Zhao

doi:10.3788/COL201412.041101

Superresolution imaging of DNA tetrahedral nanostructures in cells by STED method with continuous wave lasers

Jiancong Du
, Suhui Deng^*
, Shangguo Hou
, Lingling Qiao
, Jianfang Chen
, Qing Huang
, Chunhai Fan
, Ya Cheng
, Yun Zhao

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

DNA tetrahedral nanostructures are considered to be new nanocarriers because they can be precisely controlled and hold excellent penetration ability to the cellular membrane. Although the DNA tetrahedral nanostructure is extensively studied in biology and medicine, its behavior in the cells with nanoscale resolution is not understood clearly. In this letter, we demonstrate superresolution fluorescence imaging of the distribution of DNA tetrahedral nanostructures in the cell with a simulated emission depletion (STED) microscope, which is built based on a conventional confocal microscope and can provide a resolution of 70 nm.

Original language	English
Article number	041101
Journal	Chinese Optics Letters
Volume	12
Issue number	4
DOIs	https://doi.org/10.3788/COL201412.041101
State	Published - Apr 2014
Externally published	Yes

Access to Document

10.3788/COL201412.041101

Cite this

@article{9a6f8cddbd4445a5b0a17bd794658a51,

title = "Superresolution imaging of DNA tetrahedral nanostructures in cells by STED method with continuous wave lasers",

abstract = "DNA tetrahedral nanostructures are considered to be new nanocarriers because they can be precisely controlled and hold excellent penetration ability to the cellular membrane. Although the DNA tetrahedral nanostructure is extensively studied in biology and medicine, its behavior in the cells with nanoscale resolution is not understood clearly. In this letter, we demonstrate superresolution fluorescence imaging of the distribution of DNA tetrahedral nanostructures in the cell with a simulated emission depletion (STED) microscope, which is built based on a conventional confocal microscope and can provide a resolution of 70 nm.",

author = "Jiancong Du and Suhui Deng and Shangguo Hou and Lingling Qiao and Jianfang Chen and Qing Huang and Chunhai Fan and Ya Cheng and Yun Zhao",

year = "2014",

month = apr,

doi = "10.3788/COL201412.041101",

language = "英语",

volume = "12",

journal = "Chinese Optics Letters",

issn = "1671-7694",

publisher = "Optica Publishing Group (formerly OSA)",

number = "4",

}

TY - JOUR

T1 - Superresolution imaging of DNA tetrahedral nanostructures in cells by STED method with continuous wave lasers

AU - Du, Jiancong

AU - Deng, Suhui

AU - Hou, Shangguo

AU - Qiao, Lingling

AU - Chen, Jianfang

AU - Huang, Qing

AU - Fan, Chunhai

AU - Cheng, Ya

AU - Zhao, Yun

PY - 2014/4

Y1 - 2014/4

N2 - DNA tetrahedral nanostructures are considered to be new nanocarriers because they can be precisely controlled and hold excellent penetration ability to the cellular membrane. Although the DNA tetrahedral nanostructure is extensively studied in biology and medicine, its behavior in the cells with nanoscale resolution is not understood clearly. In this letter, we demonstrate superresolution fluorescence imaging of the distribution of DNA tetrahedral nanostructures in the cell with a simulated emission depletion (STED) microscope, which is built based on a conventional confocal microscope and can provide a resolution of 70 nm.

AB - DNA tetrahedral nanostructures are considered to be new nanocarriers because they can be precisely controlled and hold excellent penetration ability to the cellular membrane. Although the DNA tetrahedral nanostructure is extensively studied in biology and medicine, its behavior in the cells with nanoscale resolution is not understood clearly. In this letter, we demonstrate superresolution fluorescence imaging of the distribution of DNA tetrahedral nanostructures in the cell with a simulated emission depletion (STED) microscope, which is built based on a conventional confocal microscope and can provide a resolution of 70 nm.

UR - https://www.scopus.com/pages/publications/84900493395

U2 - 10.3788/COL201412.041101

DO - 10.3788/COL201412.041101

M3 - 文章

AN - SCOPUS:84900493395

SN - 1671-7694

VL - 12

JO - Chinese Optics Letters

JF - Chinese Optics Letters

IS - 4

M1 - 041101

ER -

Superresolution imaging of DNA tetrahedral nanostructures in cells by STED method with continuous wave lasers

Abstract

Access to Document

Other files and links

Fingerprint

Cite this