TY - GEN
T1 - Study on relationship between protein sequence pattern and protein secondary structure
AU - Li, Minghui
AU - Lin, Lei
AU - Wang, Xiaolong
AU - Dong, Qiwen
AU - Liu, Tao
PY - 2005
Y1 - 2005
N2 - In this paper, the relation between protein sequence pattern and protein secondary structure is studied deeply. It first introduces the protein sequence pattern and organism-specific dictionary. Then four effect factors that may affect the secondary structure of protein sequence pattern are presented. One of the factors, protein sequence segment that matches the pattern is analyzed in detail. Amino acid effect on secondary structure and effect vector are defined for the first time. Finally, the secondary structure prediction method based on the effect vector is proposed. Experimental result shows that the effect of amino acid residues on secondary structure is both position-specific and structure-specific. Amino acid effect vector is important and effective in secondary structure prediction for patterns or proteins. The prediction accuracy rate can reach 80.2% for patterns with similar secondary structures.
AB - In this paper, the relation between protein sequence pattern and protein secondary structure is studied deeply. It first introduces the protein sequence pattern and organism-specific dictionary. Then four effect factors that may affect the secondary structure of protein sequence pattern are presented. One of the factors, protein sequence segment that matches the pattern is analyzed in detail. Amino acid effect on secondary structure and effect vector are defined for the first time. Finally, the secondary structure prediction method based on the effect vector is proposed. Experimental result shows that the effect of amino acid residues on secondary structure is both position-specific and structure-specific. Amino acid effect vector is important and effective in secondary structure prediction for patterns or proteins. The prediction accuracy rate can reach 80.2% for patterns with similar secondary structures.
UR - https://www.scopus.com/pages/publications/33846929648
U2 - 10.1109/iembs.2005.1615533
DO - 10.1109/iembs.2005.1615533
M3 - 会议稿件
AN - SCOPUS:33846929648
SN - 0780387406
SN - 9780780387409
T3 - Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
SP - 4751
EP - 4754
BT - Proceedings of the 2005 27th Annual International Conference of the Engineering in Medicine and Biology Society, IEEE-EMBS 2005
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 2005 27th Annual International Conference of the Engineering in Medicine and Biology Society, IEEE-EMBS 2005
Y2 - 1 September 2005 through 4 September 2005
ER -