Abstract
The fabrication of a novel nano Ag2O2-PbO2 modified electrode is described. Hydroxide radical could be generated on the surface of the electrode at an optimized potential. Lipid peroxidate and transudatory protein were detected to show destruction of cell membrane of E. coli treated by Ag2O2-PbO2 modified electrode. DNA damage of E. coli was studied in detail with electrophoresis and DNA sequence determination. The results show that cracking of plasmid DNA and mutation of gene sequence could be induced by nano Ag2O2-PbO2 modified electrode.
| Original language | English |
|---|---|
| Pages (from-to) | 2214-2217 |
| Number of pages | 4 |
| Journal | Kao Teng Hsueh Hsiao Hua Heush Hsueh Pao/ Chemical Journal of Chinese Universities |
| Volume | 26 |
| Issue number | 12 |
| State | Published - Dec 2005 |
Keywords
- DNA damage
- E. coli
- Nano AgO-PbO modified electrode