Studies on nano Ag2O2-PbO2 modified electrode-induced cell membranes and DNA damage of E. coli

  • Jing Gu*
  • , Wen Zhang
  • , Hui Tang
  • , Li Tong Jin
  • , Yi Zuo
  • , Zi Rong Wu
  • *Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

The fabrication of a novel nano Ag2O2-PbO2 modified electrode is described. Hydroxide radical could be generated on the surface of the electrode at an optimized potential. Lipid peroxidate and transudatory protein were detected to show destruction of cell membrane of E. coli treated by Ag2O2-PbO2 modified electrode. DNA damage of E. coli was studied in detail with electrophoresis and DNA sequence determination. The results show that cracking of plasmid DNA and mutation of gene sequence could be induced by nano Ag2O2-PbO2 modified electrode.

Original languageEnglish
Pages (from-to)2214-2217
Number of pages4
JournalKao Teng Hsueh Hsiao Hua Heush Hsueh Pao/ Chemical Journal of Chinese Universities
Volume26
Issue number12
StatePublished - Dec 2005

Keywords

  • DNA damage
  • E. coli
  • Nano AgO-PbO modified electrode

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