Structure characterization of a novel neutral polysaccharide isolated from Ganoderma lucidum fruiting bodies

Deng Pan; Linqiang Wang; Congheng Chen; Baosong Teng; Chendong Wang; Zhixue Xu; Bingwen Hu; Ping Zhou

doi:10.1016/j.foodchem.2012.05.071

Structure characterization of a novel neutral polysaccharide isolated from Ganoderma lucidum fruiting bodies

Deng Pan
, Linqiang Wang
, Congheng Chen
, Baosong Teng
, Chendong Wang
, Zhixue Xu
, Bingwen Hu^*
, Ping Zhou

^*Corresponding author for this work

School of Physics and Electronic Science

Research output: Contribution to journal › Article › peer-review

103 Scopus citations

Abstract

Ganoderma lucidum (G. lucidum) is a mushroom which has been used for health promotion for a long time in China. In the present work a neutral hetero-polysaccharide, named FYGL-1, was isolated from FYGL which was reported previously capable of antihyperglycemia in vivo for further detailed chemical structure investigation. The results of monosaccharide composition and GPC analysis indicated that FYGL-1 consisted of galactose, rhamnose and glucose in mole ratio of 1.00:1.15:3.22 with a molecular weight of 78 kDa. The detailed structure of FYGL-1 was characterized by periodate oxidation, Smith degradation, methylation analysis, along with FT-IR, GC, GC-MS, 1D ¹H and ¹³C NMR and 2D NMR (HSQC, COSY, NOESY and TOCSY). Based on the analysis of the results, the structure of the repeating unit of FYGL-1 was established as.

Original language	English
Pages (from-to)	1097-1103
Number of pages	7
Journal	Food Chemistry
Volume	135
Issue number	3
DOIs	https://doi.org/10.1016/j.foodchem.2012.05.071
State	Published - 1 Dec 2012

Keywords

Ganoderma lucidum
NMR spectroscopy
Polysaccharide
Structure characterization

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10.1016/j.foodchem.2012.05.071

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title = "Structure characterization of a novel neutral polysaccharide isolated from Ganoderma lucidum fruiting bodies",

abstract = "Ganoderma lucidum (G. lucidum) is a mushroom which has been used for health promotion for a long time in China. In the present work a neutral hetero-polysaccharide, named FYGL-1, was isolated from FYGL which was reported previously capable of antihyperglycemia in vivo for further detailed chemical structure investigation. The results of monosaccharide composition and GPC analysis indicated that FYGL-1 consisted of galactose, rhamnose and glucose in mole ratio of 1.00:1.15:3.22 with a molecular weight of 78 kDa. The detailed structure of FYGL-1 was characterized by periodate oxidation, Smith degradation, methylation analysis, along with FT-IR, GC, GC-MS, 1D 1H and 13C NMR and 2D NMR (HSQC, COSY, NOESY and TOCSY). Based on the analysis of the results, the structure of the repeating unit of FYGL-1 was established as.",

keywords = "Ganoderma lucidum, NMR spectroscopy, Polysaccharide, Structure characterization",

author = "Deng Pan and Linqiang Wang and Congheng Chen and Baosong Teng and Chendong Wang and Zhixue Xu and Bingwen Hu and Ping Zhou",

year = "2012",

month = dec,

day = "1",

doi = "10.1016/j.foodchem.2012.05.071",

language = "英语",

volume = "135",

pages = "1097--1103",

journal = "Food Chemistry",

issn = "0308-8146",

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TY - JOUR

T1 - Structure characterization of a novel neutral polysaccharide isolated from Ganoderma lucidum fruiting bodies

AU - Pan, Deng

AU - Wang, Linqiang

AU - Chen, Congheng

AU - Teng, Baosong

AU - Wang, Chendong

AU - Xu, Zhixue

AU - Hu, Bingwen

AU - Zhou, Ping

PY - 2012/12/1

Y1 - 2012/12/1

N2 - Ganoderma lucidum (G. lucidum) is a mushroom which has been used for health promotion for a long time in China. In the present work a neutral hetero-polysaccharide, named FYGL-1, was isolated from FYGL which was reported previously capable of antihyperglycemia in vivo for further detailed chemical structure investigation. The results of monosaccharide composition and GPC analysis indicated that FYGL-1 consisted of galactose, rhamnose and glucose in mole ratio of 1.00:1.15:3.22 with a molecular weight of 78 kDa. The detailed structure of FYGL-1 was characterized by periodate oxidation, Smith degradation, methylation analysis, along with FT-IR, GC, GC-MS, 1D 1H and 13C NMR and 2D NMR (HSQC, COSY, NOESY and TOCSY). Based on the analysis of the results, the structure of the repeating unit of FYGL-1 was established as.

AB - Ganoderma lucidum (G. lucidum) is a mushroom which has been used for health promotion for a long time in China. In the present work a neutral hetero-polysaccharide, named FYGL-1, was isolated from FYGL which was reported previously capable of antihyperglycemia in vivo for further detailed chemical structure investigation. The results of monosaccharide composition and GPC analysis indicated that FYGL-1 consisted of galactose, rhamnose and glucose in mole ratio of 1.00:1.15:3.22 with a molecular weight of 78 kDa. The detailed structure of FYGL-1 was characterized by periodate oxidation, Smith degradation, methylation analysis, along with FT-IR, GC, GC-MS, 1D 1H and 13C NMR and 2D NMR (HSQC, COSY, NOESY and TOCSY). Based on the analysis of the results, the structure of the repeating unit of FYGL-1 was established as.

KW - Ganoderma lucidum

KW - NMR spectroscopy

KW - Polysaccharide

KW - Structure characterization

UR - https://www.scopus.com/pages/publications/84865730321

U2 - 10.1016/j.foodchem.2012.05.071

DO - 10.1016/j.foodchem.2012.05.071

M3 - 文章

C2 - 22953830

AN - SCOPUS:84865730321

SN - 0308-8146

VL - 135

SP - 1097

EP - 1103

JO - Food Chemistry

JF - Food Chemistry

IS - 3

ER -

Structure characterization of a novel neutral polysaccharide isolated from Ganoderma lucidum fruiting bodies

Abstract

Keywords

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