Structurally Well-Defined Au@Cu2-xS Core-Shell Nanocrystals for Improved Cancer Treatment Based on Enhanced Photothermal Efficiency

  • Muwei Ji
  • , Meng Xu
  • , Wei Zhang
  • , Zhenzhong Yang
  • , Liu Huang
  • , Jiajia Liu
  • , Yong Zhang
  • , Lin Gu
  • , Youxing Yu
  • , Weichang Hao
  • , Pengfei An
  • , Lirong Zheng
  • , Hesun Zhu
  • , Jiatao Zhang*
  • *Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

252 Scopus citations

Abstract

Au@Cu2-xS core-shell nanocrystals (NCs) have been synthesized under large lattice mismatch with high crystallinity, controllable shape, and nonstoichiometric composition. Both experimental observations and simulations are used to verify the flexible dual-mode plasmon coupling. The enhanced photothermal effect is harnessed for diverse HeLa cancer cell ablation applications in the NIR-I window (750-900 nm) and the NIR-II window (1000-1400 nm).

Original languageEnglish
Pages (from-to)3094-3101
Number of pages8
JournalAdvanced Materials
Volume28
Issue number16
DOIs
StatePublished - 27 Apr 2016
Externally publishedYes

Keywords

  • Au@CuS core-shell nanocrystals
  • dual-mode plasmon coupling
  • in vivo cancer treatment
  • photothermal
  • surface plasmon resonance coupling

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