Stimuli-responsive controlled drug release from a hollow mesoporous silica sphere/polyelectrolyte multilayer core-shell structure

Yufang Zhu; Jianlin Shi; Weihua Shen; Xiaoping Dong; Jingwei Feng; Meilin Ruan; Yongsheng Li

doi:10.1002/anie.200501500

Stimuli-responsive controlled drug release from a hollow mesoporous silica sphere/polyelectrolyte multilayer core-shell structure

Yufang Zhu, Jianlin Shi, Weihua Shen, Xiaoping Dong, Jingwei Feng, Meilin Ruan, Yongsheng Li

CAS - Shanghai Institute of Ceramics

Research output: Contribution to journal › Article › peer-review

961 Scopus citations

Abstract

(Figure Presented) Keeping drugs under control: Hydrothermally stable, hollow mesoporous silica spheres have a high drug storage capacity, and polyelectrolyte multilayers coated on the spheres act as a switch for drug release which is controlled by the pH or ionic strength of the release medium. The picture shows the release of ibuprofen (IBU) from spheres with and without coatings of sodium polystyrene sulfonate (PSS) and poly(allylamine hydrochloride) (PAH).

Original language	English
Pages (from-to)	5083-5087
Number of pages	5
Journal	Angewandte Chemie - International Edition
Volume	44
Issue number	32
DOIs	https://doi.org/10.1002/anie.200501500
State	Published - 12 Aug 2005
Externally published	Yes

Keywords

Drug delivery
Mesoporous materials
Multilayers
Nanostructures
Polyelectrolytes

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10.1002/anie.200501500

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title = "Stimuli-responsive controlled drug release from a hollow mesoporous silica sphere/polyelectrolyte multilayer core-shell structure",

abstract = "(Figure Presented) Keeping drugs under control: Hydrothermally stable, hollow mesoporous silica spheres have a high drug storage capacity, and polyelectrolyte multilayers coated on the spheres act as a switch for drug release which is controlled by the pH or ionic strength of the release medium. The picture shows the release of ibuprofen (IBU) from spheres with and without coatings of sodium polystyrene sulfonate (PSS) and poly(allylamine hydrochloride) (PAH).",

keywords = "Drug delivery, Mesoporous materials, Multilayers, Nanostructures, Polyelectrolytes",

author = "Yufang Zhu and Jianlin Shi and Weihua Shen and Xiaoping Dong and Jingwei Feng and Meilin Ruan and Yongsheng Li",

year = "2005",

month = aug,

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volume = "44",

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T1 - Stimuli-responsive controlled drug release from a hollow mesoporous silica sphere/polyelectrolyte multilayer core-shell structure

AU - Zhu, Yufang

AU - Shi, Jianlin

AU - Shen, Weihua

AU - Dong, Xiaoping

AU - Feng, Jingwei

AU - Ruan, Meilin

AU - Li, Yongsheng

PY - 2005/8/12

Y1 - 2005/8/12

N2 - (Figure Presented) Keeping drugs under control: Hydrothermally stable, hollow mesoporous silica spheres have a high drug storage capacity, and polyelectrolyte multilayers coated on the spheres act as a switch for drug release which is controlled by the pH or ionic strength of the release medium. The picture shows the release of ibuprofen (IBU) from spheres with and without coatings of sodium polystyrene sulfonate (PSS) and poly(allylamine hydrochloride) (PAH).

AB - (Figure Presented) Keeping drugs under control: Hydrothermally stable, hollow mesoporous silica spheres have a high drug storage capacity, and polyelectrolyte multilayers coated on the spheres act as a switch for drug release which is controlled by the pH or ionic strength of the release medium. The picture shows the release of ibuprofen (IBU) from spheres with and without coatings of sodium polystyrene sulfonate (PSS) and poly(allylamine hydrochloride) (PAH).

KW - Drug delivery

KW - Mesoporous materials

KW - Multilayers

KW - Nanostructures

KW - Polyelectrolytes

UR - https://www.scopus.com/pages/publications/23944494146

U2 - 10.1002/anie.200501500

DO - 10.1002/anie.200501500

M3 - 文章

C2 - 16015668

AN - SCOPUS:23944494146

SN - 1433-7851

VL - 44

SP - 5083

EP - 5087

JO - Angewandte Chemie - International Edition

JF - Angewandte Chemie - International Edition

IS - 32

ER -

Stimuli-responsive controlled drug release from a hollow mesoporous silica sphere/polyelectrolyte multilayer core-shell structure

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Keywords

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