Stereoselective synthesis of 3(R) and 3(S)-hydroxyeicos-4(E)-en-1-yne, a component of the marine sponge Cribrochalina vasculum

  • Wei Lu*
  • , Guang Rong Zheng
  • , Da Xin Gao
  • , Jun Chao Cai
  • *Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Stereocontrolled synthesis of 3(R) and 3(S)-hydroxyeicos-4(E)-en-1-yne has been achieved through double elimination of chloride intermediates 8 and 11, which were prepared from acetylenic alcohol intermediates 1 and 10.

Original languageEnglish
Pages (from-to)365-367
Number of pages3
JournalChinese Chemical Letters
Volume9
Issue number4
StatePublished - 1998
Externally publishedYes

Keywords

  • 3-hydroxyeicos-4(E)-en-1-yne
  • Double elimination
  • Stereocontrolled synthesis

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