Sol-gel derived mesoporous bioactive glass fibers as tissue-engineering scaffolds

Jing Yi; Guangfeng Wei; Xiaohui Huang; Lingzhi Zhao; Quan Zhang; Chengzhong Yu

doi:10.1007/s10971-007-1668-x

Sol-gel derived mesoporous bioactive glass fibers as tissue-engineering scaffolds

Jing Yi, Guangfeng Wei, Xiaohui Huang, Lingzhi Zhao, Quan Zhang, Chengzhong Yu

Research output: Contribution to journal › Article › peer-review

25 Scopus citations

Abstract

Mesoporous bioactive glass (MBG) fibers have been synthesized using the combination of a sol-gel process and a high velocity spray procedure by carefully controlling the sol composition, acidity and water content. A three-dimensional (3D) macro-structure with ∼ 50-100 μm interconnected macropores is formed in the spraying process. The MBG fibers possess well-ordered hexagonal mesostructure and excellent in vitro bioactivities. Sprague-Dawley (SD) rat osteoblasts have been cultured on MBG fibers. It is found that the MBG fibers have good cell biocompatibility and the 3D macro-structure is beneficial for cell attachment. It is anticipated that MBG fibers with controlled mesostructure and excellent in vitro bioactivity are good candidates for future tissue-engineering scaffolds.

Original language	English
Pages (from-to)	115-119
Number of pages	5
Journal	Journal of Sol-Gel Science and Technology
Volume	45
Issue number	1
DOIs	https://doi.org/10.1007/s10971-007-1668-x
State	Published - Jan 2008
Externally published	Yes

Keywords

Bioactive glass
Fibers
Mesoporous
Sol-gel
Tissue-engineering

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10.1007/s10971-007-1668-x

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abstract = "Mesoporous bioactive glass (MBG) fibers have been synthesized using the combination of a sol-gel process and a high velocity spray procedure by carefully controlling the sol composition, acidity and water content. A three-dimensional (3D) macro-structure with ∼ 50-100 μm interconnected macropores is formed in the spraying process. The MBG fibers possess well-ordered hexagonal mesostructure and excellent in vitro bioactivities. Sprague-Dawley (SD) rat osteoblasts have been cultured on MBG fibers. It is found that the MBG fibers have good cell biocompatibility and the 3D macro-structure is beneficial for cell attachment. It is anticipated that MBG fibers with controlled mesostructure and excellent in vitro bioactivity are good candidates for future tissue-engineering scaffolds.",

keywords = "Bioactive glass, Fibers, Mesoporous, Sol-gel, Tissue-engineering",

author = "Jing Yi and Guangfeng Wei and Xiaohui Huang and Lingzhi Zhao and Quan Zhang and Chengzhong Yu",

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doi = "10.1007/s10971-007-1668-x",

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T1 - Sol-gel derived mesoporous bioactive glass fibers as tissue-engineering scaffolds

AU - Yi, Jing

AU - Wei, Guangfeng

AU - Huang, Xiaohui

AU - Zhao, Lingzhi

AU - Zhang, Quan

AU - Yu, Chengzhong

PY - 2008/1

Y1 - 2008/1

N2 - Mesoporous bioactive glass (MBG) fibers have been synthesized using the combination of a sol-gel process and a high velocity spray procedure by carefully controlling the sol composition, acidity and water content. A three-dimensional (3D) macro-structure with ∼ 50-100 μm interconnected macropores is formed in the spraying process. The MBG fibers possess well-ordered hexagonal mesostructure and excellent in vitro bioactivities. Sprague-Dawley (SD) rat osteoblasts have been cultured on MBG fibers. It is found that the MBG fibers have good cell biocompatibility and the 3D macro-structure is beneficial for cell attachment. It is anticipated that MBG fibers with controlled mesostructure and excellent in vitro bioactivity are good candidates for future tissue-engineering scaffolds.

AB - Mesoporous bioactive glass (MBG) fibers have been synthesized using the combination of a sol-gel process and a high velocity spray procedure by carefully controlling the sol composition, acidity and water content. A three-dimensional (3D) macro-structure with ∼ 50-100 μm interconnected macropores is formed in the spraying process. The MBG fibers possess well-ordered hexagonal mesostructure and excellent in vitro bioactivities. Sprague-Dawley (SD) rat osteoblasts have been cultured on MBG fibers. It is found that the MBG fibers have good cell biocompatibility and the 3D macro-structure is beneficial for cell attachment. It is anticipated that MBG fibers with controlled mesostructure and excellent in vitro bioactivity are good candidates for future tissue-engineering scaffolds.

KW - Bioactive glass

KW - Fibers

KW - Mesoporous

KW - Sol-gel

KW - Tissue-engineering

UR - https://www.scopus.com/pages/publications/37749034314

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DO - 10.1007/s10971-007-1668-x

M3 - 文章

AN - SCOPUS:37749034314

SN - 0928-0707

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JO - Journal of Sol-Gel Science and Technology

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Sol-gel derived mesoporous bioactive glass fibers as tissue-engineering scaffolds

Abstract

Keywords

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