TY - JOUR
T1 - Small-molecule fluorescent probes for specific detection and imaging of chemical species inside lysosomes
AU - Zhu, Jun Long
AU - Xu, Zheng
AU - Yang, Yangyang
AU - Xu, Lin
N1 - Publisher Copyright:
© 2019 The Royal Society of Chemistry.
PY - 2019
Y1 - 2019
N2 - In the past few years, the preparation of novel small-molecule fluorescent probes for specific detection and imaging of chemical species inside lysosomes has attracted considerable attention because of their wide applications in chemistry, biology, and medical science. This feature article summarizes the recent advances in the design and preparation of small-molecule fluorescent probes for specific detection of chemical species inside lysosomes. In addition, their properties and applications for the detection and imaging of pH, H2O2, HOCl, O2-, lipid peroxidation, H2S, HSO3-, thiols, NO, ONOO-, HNO, Zn2+, Cu2+, enzymes, etc. in lysosomes are discussed as well.
AB - In the past few years, the preparation of novel small-molecule fluorescent probes for specific detection and imaging of chemical species inside lysosomes has attracted considerable attention because of their wide applications in chemistry, biology, and medical science. This feature article summarizes the recent advances in the design and preparation of small-molecule fluorescent probes for specific detection of chemical species inside lysosomes. In addition, their properties and applications for the detection and imaging of pH, H2O2, HOCl, O2-, lipid peroxidation, H2S, HSO3-, thiols, NO, ONOO-, HNO, Zn2+, Cu2+, enzymes, etc. in lysosomes are discussed as well.
UR - https://www.scopus.com/pages/publications/85066875268
U2 - 10.1039/c9cc03299a
DO - 10.1039/c9cc03299a
M3 - 文章
C2 - 31119257
AN - SCOPUS:85066875268
SN - 1359-7345
VL - 55
SP - 6629
EP - 6671
JO - Chemical Communications
JF - Chemical Communications
IS - 47
ER -