Single molecule SERS and detection of biomolecules with a single gold nanoparticle on a mirror junction

  • Li Li
  • , Tanya Hutter
  • , Ullrich Steiner
  • , Sumeet Mahajan*
  • *Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

120 Scopus citations

Abstract

Using the bianalyte method we unambiguously demonstrate that a single gold nanosphere on a metal film junction, in the so-called nanoparticle on a mirror configuration, is capable of single molecule detection with surface-enhanced Raman spectroscopy (SERS). Also this configuration serves as a convenient and highly sensitive SERS sensor for detection of biomolecules. Such simple nano-junction based systems are ideal for chemical and biomedical analysis.

Original languageEnglish
Pages (from-to)4574-4578
Number of pages5
JournalAnalyst
Volume138
Issue number16
DOIs
StatePublished - 21 Aug 2013
Externally publishedYes

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