Simultaneous electrochemical determination of ascorbic acid, dopamine and uric acid using a palladium nanoparticle/graphene/chitosan modified electrode

Xue Wang, Min Wu, Wanrong Tang, Yan Zhu, Lianwei Wang, Qingjiang Wang, Pingang He, Yuzhi Fang

Research output: Contribution to journalArticlepeer-review

175 Scopus citations

Abstract

A palladium nanoparticle/graphene/chitosan/glassy carbon electrode (PdNPs/GR/CS GCE) was prepared and characterized in this paper. This chemical modified electrode displayed excellent eletrochemical catalytic activities towards ascorbic acid (AA), dopamine (DA) and uric acid (UA) compared with bare GCE, PdNPs/GCE and GR/CS GCE by cyclic voltammetry (CV) and differential pulse voltammetry (DPV). All oxidation potentials of AA, DA and UA at the PdNPs/GR/CS GCE shifted negatively and the peak currents were much larger than other electrodes. DPV was used for simultaneous determination of AA, DA and UA in their mixture, and the peak potential separations between AA and DA, DA and UA, AA and UA were 252 mV, 144 mV and 396 mV, respectively. The limits of detection (S/N = 3) for AA, DA and UA were 20 μM, 0.1 μM and 0.17 μM, respectively. This PdNPs/GR/CS GCE showed many merits in stability, sensitivity, facility and economy.

Original languageEnglish
Pages (from-to)10-16
Number of pages7
JournalJournal of Electroanalytical Chemistry
Volume695
DOIs
StatePublished - 2013

Keywords

  • Chitosan
  • Electrochemical determination
  • Graphene
  • Palladium nanoparticles

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