Self-assembled monolayers suitable for electron-transfer promotion of copper, zinc-superoxide dismutase

Yang Tian; Takako Ariga; Noriko Takashima; Takeyoshi Okajima; Lanqun Mao; Takeo Ohsaka

doi:10.1016/j.elecom.2004.04.013

Self-assembled monolayers suitable for electron-transfer promotion of copper, zinc-superoxide dismutase

Yang Tian
, Takako Ariga
, Noriko Takashima
, Takeyoshi Okajima
, Lanqun Mao
, Takeo Ohsaka^*

^*Corresponding author for this work

Institute of Science Tokyo

Research output: Contribution to journal › Article › peer-review

55 Scopus citations

Abstract

A large variety of thiols and disulfides were studied with respect to their capability to promote the direct electrochemistry of bovine erythrocyte copper, zinc-superoxide dismutase (Cu, Zn-SOD). Experimental results strongly suggested that the electron-transfer (ET) properties of Cu, Zn-SOD remarkably depend on the structure of the promoters used, revealing the essence of structure-associated promoted ET properties of SOD. Among all the thiols and disulfides tested, the COOH-terminated aliphatic thiols and disulfides with a short alkylene chain [-(CH₂)-_n, (n=1-3)] were found to be favorable for the ET of SOD. The promoted electrochemical process and the probable explanation for the different capability of the various thiols and disulfides for promoting the ET of SOD were presented and discussed.

Original language	English
Pages (from-to)	609-614
Number of pages	6
Journal	Electrochemistry Communications
Volume	6
Issue number	6
DOIs	https://doi.org/10.1016/j.elecom.2004.04.013
State	Published - Jun 2004
Externally published	Yes

Keywords

Copper, zinc-superoxide dismutase
Electron-transfer
Promoter
Self-assembled monolayer

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10.1016/j.elecom.2004.04.013

Cite this

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title = "Self-assembled monolayers suitable for electron-transfer promotion of copper, zinc-superoxide dismutase",

abstract = "A large variety of thiols and disulfides were studied with respect to their capability to promote the direct electrochemistry of bovine erythrocyte copper, zinc-superoxide dismutase (Cu, Zn-SOD). Experimental results strongly suggested that the electron-transfer (ET) properties of Cu, Zn-SOD remarkably depend on the structure of the promoters used, revealing the essence of structure-associated promoted ET properties of SOD. Among all the thiols and disulfides tested, the COOH-terminated aliphatic thiols and disulfides with a short alkylene chain [-(CH2)-n, (n=1-3)] were found to be favorable for the ET of SOD. The promoted electrochemical process and the probable explanation for the different capability of the various thiols and disulfides for promoting the ET of SOD were presented and discussed.",

keywords = "Copper, zinc-superoxide dismutase, Electron-transfer, Promoter, Self-assembled monolayer",

author = "Yang Tian and Takako Ariga and Noriko Takashima and Takeyoshi Okajima and Lanqun Mao and Takeo Ohsaka",

year = "2004",

month = jun,

doi = "10.1016/j.elecom.2004.04.013",

language = "英语",

volume = "6",

pages = "609--614",

journal = "Electrochemistry Communications",

issn = "1388-2481",

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TY - JOUR

T1 - Self-assembled monolayers suitable for electron-transfer promotion of copper, zinc-superoxide dismutase

AU - Tian, Yang

AU - Ariga, Takako

AU - Takashima, Noriko

AU - Okajima, Takeyoshi

AU - Mao, Lanqun

AU - Ohsaka, Takeo

PY - 2004/6

Y1 - 2004/6

N2 - A large variety of thiols and disulfides were studied with respect to their capability to promote the direct electrochemistry of bovine erythrocyte copper, zinc-superoxide dismutase (Cu, Zn-SOD). Experimental results strongly suggested that the electron-transfer (ET) properties of Cu, Zn-SOD remarkably depend on the structure of the promoters used, revealing the essence of structure-associated promoted ET properties of SOD. Among all the thiols and disulfides tested, the COOH-terminated aliphatic thiols and disulfides with a short alkylene chain [-(CH2)-n, (n=1-3)] were found to be favorable for the ET of SOD. The promoted electrochemical process and the probable explanation for the different capability of the various thiols and disulfides for promoting the ET of SOD were presented and discussed.

AB - A large variety of thiols and disulfides were studied with respect to their capability to promote the direct electrochemistry of bovine erythrocyte copper, zinc-superoxide dismutase (Cu, Zn-SOD). Experimental results strongly suggested that the electron-transfer (ET) properties of Cu, Zn-SOD remarkably depend on the structure of the promoters used, revealing the essence of structure-associated promoted ET properties of SOD. Among all the thiols and disulfides tested, the COOH-terminated aliphatic thiols and disulfides with a short alkylene chain [-(CH2)-n, (n=1-3)] were found to be favorable for the ET of SOD. The promoted electrochemical process and the probable explanation for the different capability of the various thiols and disulfides for promoting the ET of SOD were presented and discussed.

KW - Copper, zinc-superoxide dismutase

KW - Electron-transfer

KW - Promoter

KW - Self-assembled monolayer

UR - https://www.scopus.com/pages/publications/2442450533

U2 - 10.1016/j.elecom.2004.04.013

DO - 10.1016/j.elecom.2004.04.013

M3 - 文章

AN - SCOPUS:2442450533

SN - 1388-2481

VL - 6

SP - 609

EP - 614

JO - Electrochemistry Communications

JF - Electrochemistry Communications

IS - 6

ER -

Self-assembled monolayers suitable for electron-transfer promotion of copper, zinc-superoxide dismutase

Abstract

Keywords

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