TY - JOUR
T1 - Self-assembled monolayers suitable for electron-transfer promotion of copper, zinc-superoxide dismutase
AU - Tian, Yang
AU - Ariga, Takako
AU - Takashima, Noriko
AU - Okajima, Takeyoshi
AU - Mao, Lanqun
AU - Ohsaka, Takeo
PY - 2004/6
Y1 - 2004/6
N2 - A large variety of thiols and disulfides were studied with respect to their capability to promote the direct electrochemistry of bovine erythrocyte copper, zinc-superoxide dismutase (Cu, Zn-SOD). Experimental results strongly suggested that the electron-transfer (ET) properties of Cu, Zn-SOD remarkably depend on the structure of the promoters used, revealing the essence of structure-associated promoted ET properties of SOD. Among all the thiols and disulfides tested, the COOH-terminated aliphatic thiols and disulfides with a short alkylene chain [-(CH2)-n, (n=1-3)] were found to be favorable for the ET of SOD. The promoted electrochemical process and the probable explanation for the different capability of the various thiols and disulfides for promoting the ET of SOD were presented and discussed.
AB - A large variety of thiols and disulfides were studied with respect to their capability to promote the direct electrochemistry of bovine erythrocyte copper, zinc-superoxide dismutase (Cu, Zn-SOD). Experimental results strongly suggested that the electron-transfer (ET) properties of Cu, Zn-SOD remarkably depend on the structure of the promoters used, revealing the essence of structure-associated promoted ET properties of SOD. Among all the thiols and disulfides tested, the COOH-terminated aliphatic thiols and disulfides with a short alkylene chain [-(CH2)-n, (n=1-3)] were found to be favorable for the ET of SOD. The promoted electrochemical process and the probable explanation for the different capability of the various thiols and disulfides for promoting the ET of SOD were presented and discussed.
KW - Copper, zinc-superoxide dismutase
KW - Electron-transfer
KW - Promoter
KW - Self-assembled monolayer
UR - https://www.scopus.com/pages/publications/2442450533
U2 - 10.1016/j.elecom.2004.04.013
DO - 10.1016/j.elecom.2004.04.013
M3 - 文章
AN - SCOPUS:2442450533
SN - 1388-2481
VL - 6
SP - 609
EP - 614
JO - Electrochemistry Communications
JF - Electrochemistry Communications
IS - 6
ER -