Reversible redox of NADH and NAD + at a hybrid lipid bilayer membrane using ubiquinone

Wei Ma; Da Wei Li; Todd C. Sutherland; Yang Li; Yi Tao Long; Hong Yuan Chen

doi:10.1021/ja204014s

Reversible redox of NADH and NAD ⁺ at a hybrid lipid bilayer membrane using ubiquinone

Wei Ma, Da Wei Li, Todd C. Sutherland, Yang Li, Yi Tao Long, Hong Yuan Chen

Research output: Contribution to journal › Article › peer-review

69 Scopus citations

Abstract

Here, we report the reversible interconversion between NADH and NAD ⁺ at a low overpotential, which is in part mediated by ubiquinone embedded in a biomimetic membrane to mimic the initial stages of respiration. This system can be used as a platform to examine biologically relevant electroactive molecules embedded in a natural membrane environment and provide new insights into the mechanism of biological redox cycling.

Original language	English
Pages (from-to)	12366-12369
Number of pages	4
Journal	Journal of the American Chemical Society
Volume	133
Issue number	32
DOIs	https://doi.org/10.1021/ja204014s
State	Published - 17 Aug 2011
Externally published	Yes

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10.1021/ja204014s

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title = "Reversible redox of NADH and NAD + at a hybrid lipid bilayer membrane using ubiquinone",

abstract = "Here, we report the reversible interconversion between NADH and NAD + at a low overpotential, which is in part mediated by ubiquinone embedded in a biomimetic membrane to mimic the initial stages of respiration. This system can be used as a platform to examine biologically relevant electroactive molecules embedded in a natural membrane environment and provide new insights into the mechanism of biological redox cycling.",

author = "Wei Ma and Li, \{Da Wei\} and Sutherland, \{Todd C.\} and Yang Li and Long, \{Yi Tao\} and Chen, \{Hong Yuan\}",

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AU - Ma, Wei

AU - Li, Da Wei

AU - Sutherland, Todd C.

AU - Li, Yang

AU - Long, Yi Tao

AU - Chen, Hong Yuan

PY - 2011/8/17

Y1 - 2011/8/17

N2 - Here, we report the reversible interconversion between NADH and NAD + at a low overpotential, which is in part mediated by ubiquinone embedded in a biomimetic membrane to mimic the initial stages of respiration. This system can be used as a platform to examine biologically relevant electroactive molecules embedded in a natural membrane environment and provide new insights into the mechanism of biological redox cycling.

AB - Here, we report the reversible interconversion between NADH and NAD + at a low overpotential, which is in part mediated by ubiquinone embedded in a biomimetic membrane to mimic the initial stages of respiration. This system can be used as a platform to examine biologically relevant electroactive molecules embedded in a natural membrane environment and provide new insights into the mechanism of biological redox cycling.

UR - https://www.scopus.com/pages/publications/80051596434

U2 - 10.1021/ja204014s

DO - 10.1021/ja204014s

M3 - 文章

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AN - SCOPUS:80051596434

SN - 0002-7863

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EP - 12369

JO - Journal of the American Chemical Society

JF - Journal of the American Chemical Society

IS - 32

ER -

Reversible redox of NADH and NAD ⁺ at a hybrid lipid bilayer membrane using ubiquinone

Abstract

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