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Reversible redox of NADH and NAD + at a hybrid lipid bilayer membrane using ubiquinone

  • Wei Ma
  • , Da Wei Li
  • , Todd C. Sutherland
  • , Yang Li
  • , Yi Tao Long*
  • , Hong Yuan Chen
  • *Corresponding author for this work
  • East China University of Science and Technology
  • University of Calgary
  • Nanjing University

Research output: Contribution to journalArticlepeer-review

Abstract

Here, we report the reversible interconversion between NADH and NAD + at a low overpotential, which is in part mediated by ubiquinone embedded in a biomimetic membrane to mimic the initial stages of respiration. This system can be used as a platform to examine biologically relevant electroactive molecules embedded in a natural membrane environment and provide new insights into the mechanism of biological redox cycling.

Original languageEnglish
Pages (from-to)12366-12369
Number of pages4
JournalJournal of the American Chemical Society
Volume133
Issue number32
DOIs
StatePublished - 17 Aug 2011
Externally publishedYes

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