Research Progresses in Single Molecule Enzymology

Yan XU; Le Le SUN; Yan Jing GAO; Wei Wei QIN; Tian Huan PENG; Di LI

doi:10.1016/S1872-2040(16)60957-X

Research Progresses in Single Molecule Enzymology

Yan XU
, Le Le SUN
, Yan Jing GAO
, Wei Wei QIN
, Tian Huan PENG
, Di LI^*

^*Corresponding author for this work

Chinese Academy of Sciences

Research output: Contribution to journal › Review article › peer-review

1 Scopus citations

Abstract

The advent of single molecule imaging technologies in 1990s made the dynamics of single molecule enzyme catalysis be successfully probed in real time in vitro. Ever since then, single molecule enzymology entered the golden age of rapid developing. Individual features of single enzyme molecule hidden in the overall average were discovered, and many new catalytic mechanisms were proposed. Single molecule enzymology sheds light on the dynamic interactions between enzyme and substrate or product, deepening the understanding of biochemical reactions.

Original language	English
Pages (from-to)	1437-1446
Number of pages	10
Journal	Chinese Journal of Analytical Chemistry
Volume	44
Issue number	9
DOIs	https://doi.org/10.1016/S1872-2040(16)60957-X
State	Published - Sep 2016
Externally published	Yes

Keywords

Enzyme
Fluorescence microscopy
Fluorescence resonance energy transfer
Review
Ribozyme
Single molecule

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10.1016/S1872-2040(16)60957-X

Cite this

@article{b45eedc87a5b4de9a4ff948cc5b7c0c5,

title = "Research Progresses in Single Molecule Enzymology",

abstract = "The advent of single molecule imaging technologies in 1990s made the dynamics of single molecule enzyme catalysis be successfully probed in real time in vitro. Ever since then, single molecule enzymology entered the golden age of rapid developing. Individual features of single enzyme molecule hidden in the overall average were discovered, and many new catalytic mechanisms were proposed. Single molecule enzymology sheds light on the dynamic interactions between enzyme and substrate or product, deepening the understanding of biochemical reactions.",

keywords = "Enzyme, Fluorescence microscopy, Fluorescence resonance energy transfer, Review, Ribozyme, Single molecule",

author = "Yan XU and SUN, \{Le Le\} and GAO, \{Yan Jing\} and QIN, \{Wei Wei\} and PENG, \{Tian Huan\} and Di LI",

note = "Publisher Copyright: {\textcopyright} 2016 Changchun Institute of Applied Chemistry, Chinese Academy of Sciences",

year = "2016",

month = sep,

doi = "10.1016/S1872-2040(16)60957-X",

language = "英语",

volume = "44",

pages = "1437--1446",

journal = "Chinese Journal of Analytical Chemistry",

issn = "0253-3820",

publisher = "Chinese Academy of Sciences",

number = "9",

}

TY - JOUR

T1 - Research Progresses in Single Molecule Enzymology

AU - XU, Yan

AU - SUN, Le Le

AU - GAO, Yan Jing

AU - QIN, Wei Wei

AU - PENG, Tian Huan

AU - LI, Di

PY - 2016/9

Y1 - 2016/9

N2 - The advent of single molecule imaging technologies in 1990s made the dynamics of single molecule enzyme catalysis be successfully probed in real time in vitro. Ever since then, single molecule enzymology entered the golden age of rapid developing. Individual features of single enzyme molecule hidden in the overall average were discovered, and many new catalytic mechanisms were proposed. Single molecule enzymology sheds light on the dynamic interactions between enzyme and substrate or product, deepening the understanding of biochemical reactions.

AB - The advent of single molecule imaging technologies in 1990s made the dynamics of single molecule enzyme catalysis be successfully probed in real time in vitro. Ever since then, single molecule enzymology entered the golden age of rapid developing. Individual features of single enzyme molecule hidden in the overall average were discovered, and many new catalytic mechanisms were proposed. Single molecule enzymology sheds light on the dynamic interactions between enzyme and substrate or product, deepening the understanding of biochemical reactions.

KW - Enzyme

KW - Fluorescence microscopy

KW - Fluorescence resonance energy transfer

KW - Review

KW - Ribozyme

KW - Single molecule

UR - https://www.scopus.com/pages/publications/85044291449

U2 - 10.1016/S1872-2040(16)60957-X

DO - 10.1016/S1872-2040(16)60957-X

M3 - 文献综述

AN - SCOPUS:85044291449

SN - 0253-3820

VL - 44

SP - 1437

EP - 1446

JO - Chinese Journal of Analytical Chemistry

JF - Chinese Journal of Analytical Chemistry

IS - 9

ER -

Research Progresses in Single Molecule Enzymology

Abstract

Keywords

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