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Representation of the signal transduction with aberrance using Ipi calculus

  • Min Zhang*
  • , Guoqiang Li
  • , Yuxi Fu
  • , Zhizhou Zhang
  • , Lin He
  • *Corresponding author for this work
  • Shanghai Jiao Tong University

Research output: Contribution to journalArticlepeer-review

Abstract

The pi calculus has been applied to modelling biochemical networks. In these applications, the modelling is done without considerations to exceptions. The Ipi calculus, the Interference pi calculus, is introduced to describe the signal transduction with aberrance. The calculus is obtained by adding two aberrant actions into the pi calculus and a tag system to check existing aberrance. A model of the signal transduction, RTK-MAPK, with the aberrant Ras is highlighted to illustrate the expressive power of the Ipi calculus.

Original languageEnglish
Pages (from-to)477-485
Number of pages9
JournalLecture Notes in Computer Science
Volume3314
DOIs
StatePublished - 2004
Externally publishedYes

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