Recent advances in the intramolecular Mannich reaction in natural products total synthesis

Yingbo Shi; Qiaoling Wang; Shuanhu Gao

doi:10.1039/c7qo01079f

Recent advances in the intramolecular Mannich reaction in natural products total synthesis

Yingbo Shi
, Qiaoling Wang^*
, Shuanhu Gao

^*Corresponding author for this work

School of Chemistry and Molecular Engineering

East China Normal University

Research output: Contribution to journal › Review article › peer-review

71 Scopus citations

Abstract

The Mannich reaction has been widely used to effectively construct C-N and C-C bonds in organic synthesis. This review focuses on selected applications of the intramolecular Mannich reaction as a key step in the total synthesis of natural products (2000-2017). The organization of the synthetic applications is based on the structure of newly-formed skeletons using the intramolecular Mannich reaction, which include aza-fused rings and aza-bridged rings.

Original language	English
Pages (from-to)	1049-1066
Number of pages	18
Journal	Organic Chemistry Frontiers
Volume	5
Issue number	6
DOIs	https://doi.org/10.1039/c7qo01079f
State	Published - 21 Mar 2018

Access to Document

10.1039/c7qo01079f

Cite this

@article{ee37bb4680ec42da91bf8f025e2d87a9,

title = "Recent advances in the intramolecular Mannich reaction in natural products total synthesis",

abstract = "The Mannich reaction has been widely used to effectively construct C-N and C-C bonds in organic synthesis. This review focuses on selected applications of the intramolecular Mannich reaction as a key step in the total synthesis of natural products (2000-2017). The organization of the synthetic applications is based on the structure of newly-formed skeletons using the intramolecular Mannich reaction, which include aza-fused rings and aza-bridged rings.",

author = "Yingbo Shi and Qiaoling Wang and Shuanhu Gao",

note = "Publisher Copyright: {\textcopyright} the Partner Organisations 2018.",

year = "2018",

month = mar,

day = "21",

doi = "10.1039/c7qo01079f",

language = "英语",

volume = "5",

pages = "1049--1066",

journal = "Organic Chemistry Frontiers",

issn = "2052-4110",

publisher = "Royal Society of Chemistry",

number = "6",

}

TY - JOUR

T1 - Recent advances in the intramolecular Mannich reaction in natural products total synthesis

AU - Shi, Yingbo

AU - Wang, Qiaoling

AU - Gao, Shuanhu

PY - 2018/3/21

Y1 - 2018/3/21

N2 - The Mannich reaction has been widely used to effectively construct C-N and C-C bonds in organic synthesis. This review focuses on selected applications of the intramolecular Mannich reaction as a key step in the total synthesis of natural products (2000-2017). The organization of the synthetic applications is based on the structure of newly-formed skeletons using the intramolecular Mannich reaction, which include aza-fused rings and aza-bridged rings.

AB - The Mannich reaction has been widely used to effectively construct C-N and C-C bonds in organic synthesis. This review focuses on selected applications of the intramolecular Mannich reaction as a key step in the total synthesis of natural products (2000-2017). The organization of the synthetic applications is based on the structure of newly-formed skeletons using the intramolecular Mannich reaction, which include aza-fused rings and aza-bridged rings.

UR - https://www.scopus.com/pages/publications/85043787922

U2 - 10.1039/c7qo01079f

DO - 10.1039/c7qo01079f

M3 - 文献综述

AN - SCOPUS:85043787922

SN - 2052-4110

VL - 5

SP - 1049

EP - 1066

JO - Organic Chemistry Frontiers

JF - Organic Chemistry Frontiers

IS - 6

ER -

Recent advances in the intramolecular Mannich reaction in natural products total synthesis

Abstract

Access to Document

Other files and links

Fingerprint

Cite this