Recent Advances in Silica‐Nanomaterial‐Assisted Lateral Flow Assay

Han Zhuang; Chun Xu; Fang Gao; Yiwei Li; Chang Lei; Chengzhong Yu

doi:10.3390/bioengineering9070266

Recent Advances in Silica‐Nanomaterial‐Assisted Lateral Flow Assay

Han Zhuang, Chun Xu, Fang Gao, Yiwei Li, Chang Lei, Chengzhong Yu

University of Queensland

Research output: Contribution to journal › Review article › peer-review

7 Scopus citations

Abstract

Lateral flow assays (LFAs) have attracted much attention as rapid and affordable point-of‐care devices for medical diagnostics. The global SARS‐CoV‐2 pandemic has further highlighted the importance of LFAs. Many efforts have been made to enhance the sensitivity of LFAs. In recent years, silica nanomaterials have been used to either amplify the signal of label materials or provide stability, resulting in better detection performance. In this review, the recent progress of silica‐na-nomaterial‐assisted LFAs is summarized. The impact of the structure of silica nanomaterials on LFA performance, the challenges and prospects in this research area are also discussed.

Original language	English
Article number	266
Journal	Bioengineering
Volume	9
Issue number	7
DOIs	https://doi.org/10.3390/bioengineering9070266
State	Published - Jul 2022
Externally published	Yes

Keywords

lateral flow assay
point‐of‐care device
signal amplification
silica nanomaterials

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10.3390/bioengineering9070266

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title = "Recent Advances in Silica‐Nanomaterial‐Assisted Lateral Flow Assay",

abstract = "Lateral flow assays (LFAs) have attracted much attention as rapid and affordable point-of‐care devices for medical diagnostics. The global SARS‐CoV‐2 pandemic has further highlighted the importance of LFAs. Many efforts have been made to enhance the sensitivity of LFAs. In recent years, silica nanomaterials have been used to either amplify the signal of label materials or provide stability, resulting in better detection performance. In this review, the recent progress of silica‐na-nomaterial‐assisted LFAs is summarized. The impact of the structure of silica nanomaterials on LFA performance, the challenges and prospects in this research area are also discussed.",

keywords = "lateral flow assay, point‐of‐care device, signal amplification, silica nanomaterials",

author = "Han Zhuang and Chun Xu and Fang Gao and Yiwei Li and Chang Lei and Chengzhong Yu",

note = "Publisher Copyright: {\textcopyright} 2022 by the authors. Licensee MDPI, Basel, Switzerland.",

year = "2022",

month = jul,

doi = "10.3390/bioengineering9070266",

language = "英语",

volume = "9",

journal = "Bioengineering",

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T1 - Recent Advances in Silica‐Nanomaterial‐Assisted Lateral Flow Assay

AU - Zhuang, Han

AU - Xu, Chun

AU - Gao, Fang

AU - Li, Yiwei

AU - Lei, Chang

AU - Yu, Chengzhong

PY - 2022/7

Y1 - 2022/7

N2 - Lateral flow assays (LFAs) have attracted much attention as rapid and affordable point-of‐care devices for medical diagnostics. The global SARS‐CoV‐2 pandemic has further highlighted the importance of LFAs. Many efforts have been made to enhance the sensitivity of LFAs. In recent years, silica nanomaterials have been used to either amplify the signal of label materials or provide stability, resulting in better detection performance. In this review, the recent progress of silica‐na-nomaterial‐assisted LFAs is summarized. The impact of the structure of silica nanomaterials on LFA performance, the challenges and prospects in this research area are also discussed.

AB - Lateral flow assays (LFAs) have attracted much attention as rapid and affordable point-of‐care devices for medical diagnostics. The global SARS‐CoV‐2 pandemic has further highlighted the importance of LFAs. Many efforts have been made to enhance the sensitivity of LFAs. In recent years, silica nanomaterials have been used to either amplify the signal of label materials or provide stability, resulting in better detection performance. In this review, the recent progress of silica‐na-nomaterial‐assisted LFAs is summarized. The impact of the structure of silica nanomaterials on LFA performance, the challenges and prospects in this research area are also discussed.

KW - lateral flow assay

KW - point‐of‐care device

KW - signal amplification

KW - silica nanomaterials

UR - https://www.scopus.com/pages/publications/85133181863

U2 - 10.3390/bioengineering9070266

DO - 10.3390/bioengineering9070266

M3 - 文献综述

AN - SCOPUS:85133181863

SN - 2306-5354

VL - 9

JO - Bioengineering

JF - Bioengineering

IS - 7

M1 - 266

ER -

Recent Advances in Silica‐Nanomaterial‐Assisted Lateral Flow Assay

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Keywords

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