Ratiometric fluorescence monitoring of cerebral Cu2+ based on coumarin-labeled DNA coupled with the Cu2+-induced oxidation of: O -phenylenediamine

Shishi Ma; Qiao Yu Zhou; Fang Ya Mu; Zi Han Chen; Xu Yin Ding; Min Zhang; Guoyue Shi

doi:10.1039/c7an01099k

Ratiometric fluorescence monitoring of cerebral Cu²⁺ based on coumarin-labeled DNA coupled with the Cu²⁺-induced oxidation of: O -phenylenediamine

Shishi Ma
, Qiao Yu Zhou
, Fang Ya Mu
, Zi Han Chen
, Xu Yin Ding
, Min Zhang^*
, Guoyue Shi

^*Corresponding author for this work

School of Chemistry and Molecular Engineering

East China Normal University

Research output: Contribution to journal › Article › peer-review

21 Scopus citations

Abstract

A novel and facile ratiometric fluorescence method for evaluating Cu²⁺ has been developed based on coumarin-labeled single-stranded DNA (C-ssDNA) coupled with the Cu²⁺-induced oxidation of o-phenylenediamine (OPD). By combining the microdialysis technique, the ratiometric fluorescence method has also been successfully exploited to monitor the cerebral Cu²⁺ in the rat brain, promising new opportunities for studying the cerebral Cu²⁺-associated physiological and pathological events.

Original language	English
Pages (from-to)	3341-3345
Number of pages	5
Journal	Analyst
Volume	142
Issue number	18
DOIs	https://doi.org/10.1039/c7an01099k
State	Published - 21 Sep 2017

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title = "Ratiometric fluorescence monitoring of cerebral Cu2+ based on coumarin-labeled DNA coupled with the Cu2+-induced oxidation of: O -phenylenediamine",

abstract = "A novel and facile ratiometric fluorescence method for evaluating Cu2+ has been developed based on coumarin-labeled single-stranded DNA (C-ssDNA) coupled with the Cu2+-induced oxidation of o-phenylenediamine (OPD). By combining the microdialysis technique, the ratiometric fluorescence method has also been successfully exploited to monitor the cerebral Cu2+ in the rat brain, promising new opportunities for studying the cerebral Cu2+-associated physiological and pathological events.",

author = "Shishi Ma and Zhou, \{Qiao Yu\} and Mu, \{Fang Ya\} and Chen, \{Zi Han\} and Ding, \{Xu Yin\} and Min Zhang and Guoyue Shi",

note = "Publisher Copyright: {\textcopyright} 2017 The Royal Society of Chemistry.",

year = "2017",

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doi = "10.1039/c7an01099k",

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T1 - Ratiometric fluorescence monitoring of cerebral Cu2+ based on coumarin-labeled DNA coupled with the Cu2+-induced oxidation of

T2 - O -phenylenediamine

AU - Ma, Shishi

AU - Zhou, Qiao Yu

AU - Mu, Fang Ya

AU - Chen, Zi Han

AU - Ding, Xu Yin

AU - Zhang, Min

AU - Shi, Guoyue

PY - 2017/9/21

Y1 - 2017/9/21

N2 - A novel and facile ratiometric fluorescence method for evaluating Cu2+ has been developed based on coumarin-labeled single-stranded DNA (C-ssDNA) coupled with the Cu2+-induced oxidation of o-phenylenediamine (OPD). By combining the microdialysis technique, the ratiometric fluorescence method has also been successfully exploited to monitor the cerebral Cu2+ in the rat brain, promising new opportunities for studying the cerebral Cu2+-associated physiological and pathological events.

AB - A novel and facile ratiometric fluorescence method for evaluating Cu2+ has been developed based on coumarin-labeled single-stranded DNA (C-ssDNA) coupled with the Cu2+-induced oxidation of o-phenylenediamine (OPD). By combining the microdialysis technique, the ratiometric fluorescence method has also been successfully exploited to monitor the cerebral Cu2+ in the rat brain, promising new opportunities for studying the cerebral Cu2+-associated physiological and pathological events.

UR - https://www.scopus.com/pages/publications/85029163576

U2 - 10.1039/c7an01099k

DO - 10.1039/c7an01099k

M3 - 文章

C2 - 28825062

AN - SCOPUS:85029163576

SN - 0003-2654

VL - 142

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JO - Analyst

JF - Analyst

IS - 18

ER -

Ratiometric fluorescence monitoring of cerebral Cu²⁺ based on coumarin-labeled DNA coupled with the Cu²⁺-induced oxidation of: O -phenylenediamine

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