Rapid Construction of Enantioenriched Benzofurochromanes by SaBOX/Copper(II) Catalyzed Enantioselective [3 + 2] Annulation of γ-Chromenes with Quinones

Yang Chen; Geng Xie Li; Ai Qing Peng; Yong Tang; Lijia Wang

doi:10.1021/acs.orglett.2c01933

Rapid Construction of Enantioenriched Benzofurochromanes by SaBOX/Copper(II) Catalyzed Enantioselective [3 + 2] Annulation of γ-Chromenes with Quinones

Yang Chen
, Geng Xie Li
, Ai Qing Peng
, Yong Tang
, Lijia Wang^*

^*Corresponding author for this work

School of Chemistry and Molecular Engineering

East China Normal University
ShanghaiTech University
CAS - Shanghai Institute of Organic Chemistry

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Abstract

A rapid construction of enantioenriched benzofurochromanes was developed by SaBOX/copper(II) catalyzed enantioselective [3 + 2] annulation of γ-chromenes with quinones. This process takes advantage of the simple starting materials and a highly efficient chiral SaBOX/copper(II) catalyst system, leading to a variety of benzofurochromanes in up to 96% yield with up to 97% ee.

Original language	English
Pages (from-to)	5525-5529
Number of pages	5
Journal	Organic Letters
Volume	24
Issue number	30
DOIs	https://doi.org/10.1021/acs.orglett.2c01933
State	Published - 5 Aug 2022

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10.1021/acs.orglett.2c01933

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title = "Rapid Construction of Enantioenriched Benzofurochromanes by SaBOX/Copper(II) Catalyzed Enantioselective [3 + 2] Annulation of γ-Chromenes with Quinones",

abstract = "A rapid construction of enantioenriched benzofurochromanes was developed by SaBOX/copper(II) catalyzed enantioselective [3 + 2] annulation of γ-chromenes with quinones. This process takes advantage of the simple starting materials and a highly efficient chiral SaBOX/copper(II) catalyst system, leading to a variety of benzofurochromanes in up to 96\% yield with up to 97\% ee.",

author = "Yang Chen and Li, \{Geng Xie\} and Peng, \{Ai Qing\} and Yong Tang and Lijia Wang",

year = "2022",

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doi = "10.1021/acs.orglett.2c01933",

language = "英语",

volume = "24",

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journal = "Organic Letters",

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T1 - Rapid Construction of Enantioenriched Benzofurochromanes by SaBOX/Copper(II) Catalyzed Enantioselective [3 + 2] Annulation of γ-Chromenes with Quinones

AU - Chen, Yang

AU - Li, Geng Xie

AU - Peng, Ai Qing

AU - Tang, Yong

AU - Wang, Lijia

PY - 2022/8/5

Y1 - 2022/8/5

N2 - A rapid construction of enantioenriched benzofurochromanes was developed by SaBOX/copper(II) catalyzed enantioselective [3 + 2] annulation of γ-chromenes with quinones. This process takes advantage of the simple starting materials and a highly efficient chiral SaBOX/copper(II) catalyst system, leading to a variety of benzofurochromanes in up to 96% yield with up to 97% ee.

AB - A rapid construction of enantioenriched benzofurochromanes was developed by SaBOX/copper(II) catalyzed enantioselective [3 + 2] annulation of γ-chromenes with quinones. This process takes advantage of the simple starting materials and a highly efficient chiral SaBOX/copper(II) catalyst system, leading to a variety of benzofurochromanes in up to 96% yield with up to 97% ee.

UR - https://www.scopus.com/pages/publications/85135596925

U2 - 10.1021/acs.orglett.2c01933

DO - 10.1021/acs.orglett.2c01933

M3 - 文章

C2 - 35876060

AN - SCOPUS:85135596925

SN - 1523-7060

VL - 24

SP - 5525

EP - 5529

JO - Organic Letters

JF - Organic Letters

IS - 30

ER -

Rapid Construction of Enantioenriched Benzofurochromanes by SaBOX/Copper(II) Catalyzed Enantioselective [3 + 2] Annulation of γ-Chromenes with Quinones

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