Rapid and sensitive fluorescent probes for monoamine oxidases B to A at low concentrations

Yexiang Zhang; Yufang Xu; Shaoying Tan; Lin Xu; Xuhong Qian

doi:10.1016/j.tetlet.2012.09.074

Rapid and sensitive fluorescent probes for monoamine oxidases B to A at low concentrations

Yexiang Zhang
, Yufang Xu
, Shaoying Tan
, Lin Xu
, Xuhong Qian^*

^*Corresponding author for this work

East China University of Science and Technology

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Abstract

A new monoamine oxidase (MAO) fluorescent probe that displays response for both monoamine oxidase type-A (MAO-A) and monoamine oxidase type-B (MAO-B) is reported. This sensing platform does not require any additional enzymes or reagents. Furthermore, the probes have better sensitivity and shorter response time by comparison with similar probes, and have potentials in differentiation of MAO-A and MAO-B upon further optimization.

Original language	English
Pages (from-to)	6881-6884
Number of pages	4
Journal	Tetrahedron Letters
Volume	53
Issue number	51
DOIs	https://doi.org/10.1016/j.tetlet.2012.09.074
State	Published - 19 Dec 2012
Externally published	Yes

Keywords

Coumarin derivatives
Fluorescent probes
Low concentrations
Monoamine oxidase type-B

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10.1016/j.tetlet.2012.09.074

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title = "Rapid and sensitive fluorescent probes for monoamine oxidases B to A at low concentrations",

abstract = "A new monoamine oxidase (MAO) fluorescent probe that displays response for both monoamine oxidase type-A (MAO-A) and monoamine oxidase type-B (MAO-B) is reported. This sensing platform does not require any additional enzymes or reagents. Furthermore, the probes have better sensitivity and shorter response time by comparison with similar probes, and have potentials in differentiation of MAO-A and MAO-B upon further optimization.",

keywords = "Coumarin derivatives, Fluorescent probes, Low concentrations, Monoamine oxidase type-B",

author = "Yexiang Zhang and Yufang Xu and Shaoying Tan and Lin Xu and Xuhong Qian",

year = "2012",

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doi = "10.1016/j.tetlet.2012.09.074",

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pages = "6881--6884",

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TY - JOUR

T1 - Rapid and sensitive fluorescent probes for monoamine oxidases B to A at low concentrations

AU - Zhang, Yexiang

AU - Xu, Yufang

AU - Tan, Shaoying

AU - Xu, Lin

AU - Qian, Xuhong

PY - 2012/12/19

Y1 - 2012/12/19

N2 - A new monoamine oxidase (MAO) fluorescent probe that displays response for both monoamine oxidase type-A (MAO-A) and monoamine oxidase type-B (MAO-B) is reported. This sensing platform does not require any additional enzymes or reagents. Furthermore, the probes have better sensitivity and shorter response time by comparison with similar probes, and have potentials in differentiation of MAO-A and MAO-B upon further optimization.

AB - A new monoamine oxidase (MAO) fluorescent probe that displays response for both monoamine oxidase type-A (MAO-A) and monoamine oxidase type-B (MAO-B) is reported. This sensing platform does not require any additional enzymes or reagents. Furthermore, the probes have better sensitivity and shorter response time by comparison with similar probes, and have potentials in differentiation of MAO-A and MAO-B upon further optimization.

KW - Coumarin derivatives

KW - Fluorescent probes

KW - Low concentrations

KW - Monoamine oxidase type-B

UR - https://www.scopus.com/pages/publications/84869234492

U2 - 10.1016/j.tetlet.2012.09.074

DO - 10.1016/j.tetlet.2012.09.074

M3 - 文章

AN - SCOPUS:84869234492

SN - 0040-4039

VL - 53

SP - 6881

EP - 6884

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 51

ER -

Rapid and sensitive fluorescent probes for monoamine oxidases B to A at low concentrations

Abstract

Keywords

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