Raman/fluorescence dual-sensing and imaging of intracellular pH distribution

Yue Cao, Ruo Can Qian, Da Wei Li, Yi Tao Long

Research output: Contribution to journalArticlepeer-review

35 Scopus citations

Abstract

Herein, a pH-sensitive probe has been designed based on DNA modified gold nanoparticles (AuNPs) for Raman/fluorescence dual-imaging of the intracellular pH distribution. In the acidic environment of cancer cells, the configuration change of DNA on the probe surface could turn "on" Raman/fluorescence signals simultaneously.

Original languageEnglish
Pages (from-to)17584-17587
Number of pages4
JournalChemical Communications
Volume51
Issue number99
DOIs
StatePublished - 2015
Externally publishedYes

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